SCHEMBL45326

SCHEMBL45326

CCCCCCCCCF

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
THRB P10828 1/20 0.61
DNM1 Q05193 9/20 0.53
ALDH1A1 P00352 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
EPHX1 P07099 1/20 0.53
LMNA P02545 2/20 0.44
HSD17B10 Q99714 1/20 0.44
SLC22A1 O15245 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4892627 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL294511 1.00
SCHEMBL19221488 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL10608047 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL113425 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL30108 1.00
SCHEMBL9938856 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL7198783 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL20966349 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1MEN1
SCHEMBL1425429 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192679-A Ink, film, light-emitting device and display device 广东聚华印刷显示技术有限公司 2025-06-24 CN claimed
WO-2024196936-A2 LOCALIZED HIGH CONCENTRATION ELECTROLYTE AND LITHIUM-ION BATTERY COMPRISING THE SAME SILA NANOTECHNOLOGIES, INC. (US) 2024-09-26 WO claimed
US-20240322244-A1 LOCALIZED HIGH CONCENTRATION ELECTROLYTE AND LITHIUM-ION BATTERY COMPRISING THE SAME SILA NANOTECHNOLOGIES, INC. 2024-09-26 US claimed
CN-113947862-B Aircraft electrical fire early warning method 西北工业大学 2022-12-27 CN claimed
CN-113947862-A Aircraft electrical fire early warning method 西北工业大学 2022-01-18 CN claimed
US-20080119493-A1 5,6-Dialkyl-7-Aminotriazolopyrimidines, their Preparation and their Use for Controlling Harmful Fungi, and Compositions Comprising these Compounds BASF AKTIENGESELLSCHAFT (DE) 2008-05-22 US claimed
US-6143939-A CONTACTING HALOGENATED COMPOUNDS WITH DIAMONDS FOR A SUFFICIENT TIME AND AT A SUFFICIENT TEMPERATURE TO CONVERT THE HALOGENATED COMPOUNDS TO OLEFINS AND HALOGENATED OLEFINS VIA ELIMINATION REACTIONS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 2000-11-07 US claimed
CN-120192679-A Ink, film, light-emitting device and display device 广东聚华印刷显示技术有限公司 2025-06-24 CN disclosed
US-12146134-B2 Microfluidic devices and methods of use in the formation and control of nanoreactors BIO-RAD LABORATORIES, INC. (US) 2024-11-19 US disclosed
WO-2024196936-A2 LOCALIZED HIGH CONCENTRATION ELECTROLYTE AND LITHIUM-ION BATTERY COMPRISING THE SAME SILA NANOTECHNOLOGIES, INC. (US) 2024-09-26 WO disclosed
US-20240322244-A1 LOCALIZED HIGH CONCENTRATION ELECTROLYTE AND LITHIUM-ION BATTERY COMPRISING THE SAME SILA NANOTECHNOLOGIES, INC. 2024-09-26 US disclosed
CN-116063345-B Phosphonic acid group monomer and preparation method thereof 中国石油化工股份有限公司 2024-08-06 CN disclosed
CN-116063626-B Anti-calcium shrinkage and expansion agent and preparation method and application thereof 中国石油化工股份有限公司 2024-05-07 CN disclosed
EP-0264104-A2 Electrophotographic photosensitive member having an overcoat layer Minolta Camera Kabushiki Kaisha (JP) 1988-04-20 EP disclosed
EP-0262570-A2 Photosensitive member comprising charge generating layer and charge transporting layer Minolta Camera Kabushiki Kaisha (JP) 1988-04-06 EP disclosed
EP-0261654-A2 Photosensitive member comprising charge generating layer and charge transporting layer Minolta Camera Kabushiki Kaisha (JP) 1988-03-30 EP disclosed
EP-0253279-A2 Photosensitive member comprising charge generating layer and charge transporting layer Minolta Camera Kabushiki Kaisha (JP) 1988-01-20 EP disclosed
US-4693799-A LOW TEMPERATURE PULSE DISCHARGING JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-09-15 US disclosed
US-4046819-A Alkylation of alkyl, cycloalkyl and aralkyl halides UOP INC. (US) 1977-09-06 US disclosed
US-3933889-A 4,5-Cis-didehydro-PGF1.sub.α analogs THE UPJOHN COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080119493-A1 5,6-Dialkyl-7-Aminotriazolopyrimidines, their Preparation and their Use for Controlling Harmful Fungi, and Compositions Comprising these Compounds DPM1, ALKBH5, DERA TSHR 3758/4885THRB 3385/4885DNM1 2636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.