SCHEMBL453285

SCHEMBL453285

O=C(O)c1ccccc1N=Nc1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDE P14735 1/20 1.00
KMT2A Q03164 9/20 0.68
MEN1 O00255 8/20 0.68
MAPT P10636 5/20 0.68
MYC P01106 1/20 0.67
NPC1 O15118 1/20 0.59
NPSR1 Q6W5P4 3/20 0.58
GAA P10253 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
TDP1 Q9NUW8 3/20 0.56
THRB P10828 2/20 0.56
PSMD14 O00487 1/20 0.56
HSP90AA1 P07900 1/20 0.56
MMP2 P08253 1/20 0.56
MAPK1 P28482 1/20 0.56
POLB P06746 2/20 0.50
TRPA1 O75762 1/20 0.48
CCNE2 O96020 1/20 0.47
CCNE1 P24864 1/20 0.47
CDK2 P24941 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401042 1.00 IDE (1.00) IDEKMT2AMEN1MAPTMYC
SCHEMBL453284 1.00 IDE (1.00) IDEKMT2AMEN1MAPTMYC
SCHEMBL12100493 1.00 IDE (1.00) IDEKMT2AMEN1MAPTMYC
SCHEMBL30884072 0.89 IDE (0.79) IDEKMT2AMEN1MAPTMYC
SCHEMBL28903951 0.89 IDE (0.79) IDEKMT2AMEN1MAPTMYC
SCHEMBL2481541 0.89 IDE (0.79) IDEKMT2AMEN1MAPTMYC
SCHEMBL169230 0.89 IDE (0.79) IDEKMT2AMEN1MAPTMYC
Phenol SCHEMBL7057355 0.89 IDE (0.79) IDEKMT2AMEN1MAPTMYC
SCHEMBL28229539 0.87 IDE (0.77) IDEKMT2AMEN1MAPTMYC
SCHEMBL28229538 0.87 IDE (0.77) IDEKMT2AMEN1MAPTMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119395003-A Kit, microfluidic device and method for performing biotin assays 美国西门子医学诊断股份有限公司 2025-02-07 CN claimed
US-20250027947-A1 KITS, MICROFLUIDICS DEVICES, AND METHODS FOR PERFORMING BIOTIN ASSAYS SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2025-01-23 US claimed
CN-112424589-B Kit, microfluidic device and method for performing biotin assays 美国西门子医学诊断股份有限公司 2025-01-14 CN claimed
US-12168801-B1 Hybrid/capture probe designs for full-length cDNA 10X GENOMICS, INC. (US) 2024-12-17 US claimed
US-20240399022-A1 COMPOSITIONS AND METHODS FOR MACROPHAGE CONVERSION UNIV DREXEL (US) 2024-12-05 US claimed
EP-3830556-B1 KITS, MICROFLUIDICS DEVICES, AND METHODS FOR PERFORMING BIOTIN ASSAYS SIEMENS HEALTHCARE DIAGNOSTICS INC (US) 2024-11-13 EP claimed
US-12140596-B2 Kits, microfluidics devices, and methods for performing biotin assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2024-11-12 US claimed
CN-112703401-B Methods and compositions for removing biotin interference from assays using conjugated molecular traps 美国西门子医学诊断股份有限公司 2024-10-11 CN claimed
US-12077819-B2 Compositions and processes for improved mass spectrometry analysis AGENA BIOSCIENCE, INC. (US) 2024-09-03 US claimed
US-20240096612-A1 METHOD FOR MASS SPECTROMETRY OF ORGANIC SYNTHETIC COMPOUND SHIMADZU CORPORATION (JP) 2024-03-21 US claimed
US-5763191-A BINDING MATRIX BOEHRINGER MANNHEIM GMBH (DE) 1998-06-09 US claimed
EP-0692033-B1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECH GROUP (GB) 1998-03-11 EP claimed
WO-1996033797-A1 MATRIX-BEARING TARGETS FOR MALDI MASS SPECTROMETRY AND METHODS OF PRODUCTION THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1996-10-31 WO claimed
US-5512451-A MIXTURE OF A AROMATIC DIACYL CYCLIC HYDRAZIDE, PEROXIDASE CATALYST AND OXIDIZER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US claimed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO claimed
EP-0571087-A1 Cleavable phosphoramidites ROHM AND HAAS COMPANY (US) 1993-11-24 EP claimed
EP-0210449-B1 PROLONGED CHEMILUMINESCENCE MILES INC. (US) 1993-07-28 EP claimed
US-4950588-A DETECTION OF NUCLEIC ACID HYBRIDS, ANTIBODIES ANTIGENS MOLECULAR DIAGNOSTICS, INC. (US) 1990-08-21 US claimed
EP-0210449-A2 Prolonged chemiluminescence MILES INC. (US) 1987-02-04 EP claimed
EP-0116454-A2 Enhanced luminescent or luminometric assay NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-08-22 EP claimed