SCHEMBL453314

SCHEMBL453314

O=C(O)CNCc1cn([C@@H]2O[C@H](CS)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DNPH1 O43598 1/20 0.48
PYGM P11217 3/20 0.47
TK2 O00142 2/20 0.43
P2RY2 P41231 2/20 0.42
P2RY6 Q15077 2/20 0.40
P2RY14 Q15391 2/20 0.40
NT5E P21589 1/20 0.40
TYMP P19971 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18503558 0.90 PYGM (0.58) DNPH1PYGMTK2P2RY2TYMP
SCHEMBL41270 0.90 PYGM (0.58) DNPH1PYGMTK2P2RY2TYMP
SCHEMBL63573 0.90 PYGM (0.58) DNPH1PYGMTK2P2RY2TYMP
SCHEMBL14853731 0.90 PYGM (0.58) DNPH1PYGMTK2P2RY2TYMP
SCHEMBL18573807 0.90 PYGM (0.58) DNPH1PYGMTK2P2RY2TYMP
SCHEMBL18512960 0.90 PYGM (0.58) DNPH1PYGMTK2P2RY2TYMP
SCHEMBL18464475 0.89 PYGM (0.49) DNPH1PYGMTK2P2RY2P2RY6
SCHEMBL3470678 0.87 DNPH1 (0.53) DNPH1PYGMP2RY6P2RY14NT5E
SCHEMBL16807578 0.84 DNPH1 (0.44) DNPH1PYGMTK2P2RY2P2RY6
SCHEMBL3470573 0.84 DNPH1 (0.72) DNPH1P2RY2P2RY6P2RY14NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2640852-A1 SIGNAL AMPLIFICATION Speedx Pty Ltd (AU) 2013-09-25 EP claimed
US-8394946-B2 Multicomponent nucleic acid enzymes and methods for their use SPEEDX PTY LTD (AU) 2013-03-12 US claimed
WO-2012065231-A1 SIGNAL AMPLIFICATION SPEEDX PTY LTD (AU) 2012-05-24 WO claimed
EP-1948822-A1 MULTICOMPONENT NUCLEIC ACID ENZYMES AND METHODS FOR THEIR USE JOHNSON & JOHNSON RESEARCH PTY LIMITED (AU) 2008-07-30 EP claimed
US-20070231810-A1 Multicomponent nucleic acid enzymes and methods for their use SPEEDX PTY LTD (AU) 2007-10-04 US claimed
WO-2007041774-A1 MULTICOMPONENT NUCLEIC ACID ENZYMES AND METHODS FOR THEIR USE JOHNSON & JOHNSON RESEARCH PTY LIMITED (AU) 2007-04-19 WO claimed
WO-2026102473-A1 TEMPERATURE DEPENDENT PROBES FOR TARGET DETECTION SPEEDX PTY LTD (AU) 2026-05-21 WO disclosed
EP-4713476-A1 TARGET DETECTION USING TEMPERATURE CONTROLLED PROBES Speedx Pty Ltd (AU) 2026-03-25 EP disclosed
EP-3610036-B1 DETECTION CASCADES SPEEDX PTY LTD (AU) 2025-07-02 EP disclosed
US-12163182-B2 Multiplex detection of nucleic acids SPEEDX PTY LTD (AU) 2024-12-10 US disclosed
WO-2024234030-A1 TARGET DETECTION USING TEMPERATURE CONTROLLED PROBES SPEEDX PTY LTD (AU) 2024-11-21 WO disclosed
US-12123051-B2 Nucleic acid ratio determination SPEEDX PTY LTD (AU) 2024-10-22 US disclosed
CN-111492434-B Determination of nucleic acid ratio 斯皮德斯私人有限公司 2024-04-19 CN disclosed
EP-1512748-A1 O-methyltransferases of tetrahydrobenzylisoquinoline alkaloid biosynthesis in papaver somniferum Johnson & Johnson Research Pty Limited (AU) 2005-03-09 EP disclosed
EP-1401853-A4 MODULATORS OF PHARMACOLOGICAL AGENTS UNIV DUKE (US) 2004-12-15 EP disclosed
EP-1401853-A1 MODULATORS OF PHARMACOLOGICAL AGENTS DUKE UNIVERSITY (US) 2004-03-31 EP disclosed
US-20030083294-A1 Enhancing or inhibiting the biological activity of nucleic acid ligands by administrating a modulator, to change the binding of the nucleic acid ligand for its target or degrading or cleaving REGADO BIOSCIENCES, INC. 2003-05-01 US disclosed
WO-2002096926-A1 MODULATORS OF PHARMACOLOGICAL AGENTS DUKE UNIVERSITY (US) 2002-12-05 WO disclosed
US-20020137135-A1 Novel NPG-1 gene that is differentially expressed in prostate tumors BETH ISRAEL DEACONESS MEDICAL CENTER, INC., A MASSACHUSETTS CORPORATION 2002-09-26 US disclosed
US-6287777-B1 SEVERAL GENES EXPRESSED DIFFERENTIALLY BETWEEN THE HUMAN PROSTATE CARCINOMA CELL LINES LNCAP AND PC-3, WHICH ARE ANDROGEN-DEPENDENT AND ANDROGEN-INDEPENDENT, RESPECTIVELY, HAVE NOW BEEN ISOLATED. ONE OF THESE GENES, DESIGNATED NPG-1. BETH ISRAEL DEACONESS MEDICAL CENTER 2001-09-11 US disclosed