SCHEMBL453324

SCHEMBL453324

CCOC(=O)CC(=O)O[Si](C)(C)C

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.68
MGAM O43451 1/20 0.68
SI P14410 1/20 0.68
MGAM2 Q2M2H8 1/20 0.68
ALDH1A1 P00352 4/20 0.44
TRPA1 O75762 1/20 0.44
CYP1A2 P05177 1/20 0.39
LMNA P02545 2/20 0.39
HSD17B10 Q99714 1/20 0.39
PKM P14618 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 2/20 0.37
SOAT1 P35610 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1978172 0.85 MGAM (0.41) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1331824 0.83 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL8636 0.83 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1330550 0.83 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1864301 0.83 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL1331187 0.83 GAA (1.00) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL19858542 0.82 CYP1A2 (0.48) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL17433571 0.80 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL11027431 0.80 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1
Malonic Acid Diethyl Ester SCHEMBL4334303 0.80 GAA (0.94) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260117617-A1 EXPANDABLE POLYMER GROUT FOR SAND CONTROL IN A WELL CHEVRON USA INC (US) 2026-04-30 US disclosed
US-12612839-B1 Expandable polymer grout for sand control in a well CHEVRON U.S.A. INC. (US) 2026-04-28 US disclosed
EP-3898205-B1 SURFACE TREATMENT TO ENHANCE BONDING OF COMPOSITE MATERIALS CYTEC IND INC (US) 2026-03-11 EP disclosed
US-20260063011-A1 EXPANDABLE POLYMER GROUT FOR WELLBORE APPLICATIONS CHEVRON USA INC (US) 2026-03-05 US disclosed
US-12428931-B2 Cement top jobs in wellbore annuli using expandable compositions CHEVRON U.S.A. INC. (US) 2025-09-30 US disclosed
US-20250250878-A1 EXPANDABLE POLYMER GROUT FOR SEALING SUBTERRANEAN FORMATIONS CHEVRON U.S.A. INC. 2025-08-07 US disclosed
US-12378842-B1 Expandable polymer grout for sealing subterranean formations CHEVRON U.S.A. INC. (US) 2025-08-05 US disclosed
US-12134950-B2 Deployment methods for expandable polymer grout for plug and abandonment applications CHEVRON U.S.A. INC. (US) 2024-11-05 US disclosed
US-20240191594-A1 Cement Top Jobs In Wellbore Annuli Using Expandable Compositions CHEVRON U.S.A. INC. 2024-06-13 US disclosed
US-20240026206-A1 METHODS OF USING EXPANDABLE POLYMER GROUT FOR PLUG AND ABANDONMENT APPLICATIONS CHEVRON AUSTRALIA PTY LTD (AU) 2024-01-25 US disclosed
US-6248739-B1 DNA POLYMERASE INHIBITORS EFFECTIVE AGAINST HERPESVIRUSES PHARMACIA & UPJOHN COMPANY 2001-06-19 US disclosed
US-6239142-B1 HERPES VIRUS INFECTION PHARMACIA & UPJOHN COMPANY 2001-05-29 US disclosed
WO-2001025239-A2 OXAZINOQUINOLONES USEFUL FOR THE TREATMENT OF VIRAL INFECTIONS PHARMACIA & UPJOHN COMPANY (US) 2001-04-12 WO disclosed
WO-2000053610-A2 4-OXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 2000-09-14 WO disclosed
WO-2000040563-A1 4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 2000-07-13 WO disclosed
US-5464796-A Bactericides and feed additives BAYER AKTIENGESELLSCHAFT (DE) 1995-11-07 US disclosed
EP-0520240-A1 7-Isoindolinyl-quinolone and naphthyridonecarboxylic acid derivatives BAYER AG (DE) 1992-12-30 EP disclosed
EP-0043630-B1 IMPROVED PROCESS FOR THE SILYLATION OF ORGANIC COMPOUNDS WITH 1,1,1-TRIMETHYL-N-(TRIMETHYLSILYL)SILANAMINE BY MEANS OF CATALYSIS WITH CERTAIN NITROGEN CONTAINING COMPOUNDS GIST-BROCADES N.V. (NL) 1986-01-08 EP disclosed
US-4400509-A WITH HEXAMETHYLDISILANE WITH AN ORGANONITROGEN CATALYST GIST-BROCADES N.V. (NL) 1983-08-23 US disclosed
EP-0043630-A2 Improved process for the silylation of organic compounds with 1,1,1-trimethyl-N-(trimethylsilyl)silanamine by means of catalysis with certain nitrogen containing compounds GIST-BROCADES N.V. (NL) 1982-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260063011-A1 EXPANDABLE POLYMER GROUT FOR WELLBORE APPLICATIONS HPSE, HIRIP3, WEE2 GAA 2489/4885MGAM 199/4885SI 1711/4885
US-12612839-B1 Expandable polymer grout for sand control in a well GET3, USE1, WEE2 GAA 1792/4885MGAM 715/4885SI 537/4885
US-20260117617-A1 EXPANDABLE POLYMER GROUT FOR SAND CONTROL IN A WELL GET3, WEE1, WEE2 GAA 1815/4885MGAM 605/4885SI 407/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.