SCHEMBL4533455

SCHEMBL4533455

Clc1[c]n(Cl)c2cccc(Cl)c12

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6160593 0.70 GPR3 (0.36) CYP1A2CYP2A6POLB
SCHEMBL11605725 0.62 POLB (0.34) CYP1A2CYP2A6POLBLMNATSHR
SCHEMBL10832749 0.61 GRM2 (0.36) CYP1A2CYP2A6LMNA
SCHEMBL14375343 0.58 CYP1A2 (0.65) CYP1A2CYP2A6LMNATSHR
SCHEMBL4103602 0.58 TSHR (0.53) CYP1A2CYP2A6POLBLMNATSHR
SCHEMBL29620230 0.58 TSHR (0.53) CYP1A2CYP2A6POLBLMNATSHR
SCHEMBL29620231 0.58 TSHR (0.53) CYP1A2CYP2A6POLBLMNATSHR
SCHEMBL528105 0.56 CYP2A6 (0.52) CYP1A2CYP2A6LMNATSHR
SCHEMBL32666063 0.56 CYP2A6 (0.52) CYP1A2CYP2A6LMNATSHR
SCHEMBL23937812 0.56 HTR2A (0.46) LMNATSHRNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318452-B2 Solid culture medium for the detection and/or the species discrimination of glycopeptide-resistant enterococci RAMBACH ALAIN (FR) 2012-11-27 US claimed
US-20090280524-A1 SOLID CULTURE MEDIUM FOR THE DETECTION AND/OR THE SPECIES DISCRIMINATION OF GLYCOPEPTIDE-RESISTANT ENTEROCOCCI RAMBACH ALAIN 2009-11-12 US claimed
US-20140342385-A1 MEDIUM AND METHOD FOR DETECTING PATHOGENIC YERSINIA ENTEROCOLITICA BACTERIA RAMBACH ALAIN (FR) 2014-11-20 US disclosed
US-8318452-B2 Solid culture medium for the detection and/or the species discrimination of glycopeptide-resistant enterococci RAMBACH ALAIN (FR) 2012-11-27 US disclosed
US-20090280524-A1 SOLID CULTURE MEDIUM FOR THE DETECTION AND/OR THE SPECIES DISCRIMINATION OF GLYCOPEPTIDE-RESISTANT ENTEROCOCCI RAMBACH ALAIN 2009-11-12 US disclosed