SCHEMBL528105

SCHEMBL528105

Clc1c(Cl)c(Cl)c2c(Cl)cccc2c1Cl

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.52
CYP1A2 P05177 3/20 0.52
AHR P35869 3/20 0.42
NR4A2 P43354 2/20 0.41
TSHR P16473 3/20 0.39
LMNA P02545 1/20 0.38
PNMT P11086 1/20 0.36
DAO P14920 1/20 0.35
CHEK1 O14757 1/20 0.34
FLT3 P36888 1/20 0.34
PLK3 Q9H4B4 1/20 0.34
MAPK1 P28482 1/20 0.34
MCL1 Q07820 1/20 0.34
GPR84 Q9NQS5 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32666063 1.00 CYP2A6 (0.52) CYP2A6CYP1A2AHRNR4A2TSHR
SCHEMBL13121562 0.89 CYP2A6 (0.58) CYP2A6CYP1A2AHRNR4A2TSHR
SCHEMBL11530157 0.82 CYP1A2 (0.50) CYP2A6CYP1A2AHRNR4A2TSHR
SCHEMBL14375343 0.77 CYP1A2 (0.65) CYP2A6CYP1A2AHRNR4A2TSHR
SCHEMBL20356043 0.77 CYP2A6 (0.50) CYP2A6CYP1A2AHRNR4A2TSHR
SCHEMBL29635113 0.77 CYP2A6 (0.50) CYP2A6CYP1A2AHRNR4A2TSHR
SCHEMBL20356028 0.75 CYP1A2 (0.48) CYP2A6CYP1A2AHRNR4A2TSHR
SCHEMBL11328882 0.75 TSHR (0.46) CYP2A6CYP1A2TSHRMAPK1MCL1
SCHEMBL9146368 0.73 CYP2A6 (0.40) CYP2A6CYP1A2AHRTSHRMAPK1
SCHEMBL4268573 0.72 CYP2A6 (0.48) CYP2A6CYP1A2TSHRMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 946 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3898088-B1 ABRASIVE ARTICLE WITH MICROPARTICLE-COATED ABRASIVE GRAINS 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-01-28 EP claimed
US-12304028-B2 Abrasive article with microparticle-coated abrasive grains 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-05-20 US claimed
US-20220001514-A1 ABRASIVE ARTICLE WITH MICROPARTICLE-COATED ABRASIVE GRAINS 3M INNOVATIVE PROPERTIES COMPANY 2022-01-06 US claimed
EP-3898088-A1 ABRASIVE ARTICLE WITH MICROPARTICLE-COATED ABRASIVE GRAINS 3M Innovative Properties Company (US) 2021-10-27 EP claimed
WO-2020128783-A1 ABRASIVE ARTICLE WITH MICROPARTICLE-COATED ABRASIVE GRAINS 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-06-25 WO claimed
CN-110871410-A Structural type coated abrasive tool with gap 淄博理研泰山涂附磨具有限公司 2020-03-10 CN claimed
CN-102359994-B Detection method for polychlorinated naphthalene content in electronic and electrical product rubber part INSPECTION & QUARANTINE TECH CT OF GUANGDONG ENTRY EXIT INSPECTION & QUARANTINE BUREAU 2014-01-08 CN claimed
CN-102359994-A Detection method for polychlorinated naphthalene content in electronic and electrical product rubber part INSPECTION & QUARANTINE TECH CT OF GUANGDONG ENTRY EXIT INSPECTION & QUARANTINE BUREAU 2012-02-22 CN claimed
EP-1011926-A1 ROTARY BRISTLE TOOL WITH PREFERENTIALLY ORIENTED BRISTLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-06-28 EP claimed
WO-1999003643-A1 ROTARY BRISTLE TOOL WITH PREFERENTIALLY ORIENTED BRISTLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-01-28 WO claimed
US-20260145300-A1 ABRASIVE ARTICLES AND METHODS OF MAKING AND USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-05-28 US disclosed
US-12629798-B2 Abrasive articles and method of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-05-19 US disclosed
US-12595402-B2 Shaped abrasive particles with low roundness factor 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-07 US disclosed
EP-4103356-B1 COATED ABRASIVE ARTICLE AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-01 EP disclosed
US-12589467-B2 Coated abrasive articles and methods of making and using the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-03-31 US disclosed
US-4824956-A Reductive dehalogenation of halogen compounds BASF AKTIENGESELLSCHAFT (DE) 1989-04-25 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260145300-A1 ABRASIVE ARTICLES AND METHODS OF MAKING AND USING THE SAME PRPF40A, PUF60, GIGYF2 CYP2A6 2934/4885CYP1A2 2362/4885AHR 2776/4885
US-12595402-B2 Shaped abrasive particles with low roundness factor FLNA, ITGA1, YWHAZ CYP2A6 3415/4885CYP1A2 2891/4885AHR 2403/4885
US-12629798-B2 Abrasive articles and method of making the same DCX, ITGA1, FN1 CYP2A6 4813/4885CYP1A2 4649/4885AHR 4665/4885
US-12589467-B2 Coated abrasive articles and methods of making and using the same ITGAV, ITGA2B, CD47 CYP2A6 3716/4885CYP1A2 4370/4885AHR 4060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.