SCHEMBL4533549

SCHEMBL4533549

Fc1ccccc1C1CNCCN1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM1B Q8NB78 1/20 0.40
HTR2C P28335 2/20 0.40
HTR2B P41595 2/20 0.40
HTR2A P28223 1/20 0.40
CHRNB2 P17787 1/20 0.39
CHRNA4 P43681 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
HTR1A P08908 2/20 0.36
SLC6A2 P23975 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30397619 1.00 KDM1A (0.40) KDM1AMEN1KMT2AKDM1BHTR2C
SCHEMBL9786158 1.00 KDM1A (0.40) KDM1AMEN1KMT2AKDM1BHTR2C
Hydrochloric Acid SCHEMBL25219315 0.98 MEN1 (0.39) KDM1AMEN1KMT2AKDM1BHTR2C
SCHEMBL14832162 0.86 SLC6A2 (0.40) HTR2CHTR2BHTR2ACHRNB2CHRNA4
SCHEMBL27201520 0.83 HTR2C (0.38) KDM1AHTR2CHTR2BCHRNB2CHRNA4
SCHEMBL31444395 0.83 HTR2C (0.38) HTR2CHTR2BHTR2ACHRNB2CHRNA4
SCHEMBL12536769 0.81 KDM1A (0.43) KDM1AMEN1KMT2AKDM1BCHRNB2
SCHEMBL15039592 0.81 KDM1A (0.43) KDM1AMEN1KMT2AKDM1BCHRNB2
SCHEMBL14831634 0.79 CHRNB2 (0.43) HTR2CHTR2BHTR2ACHRNB2CHRNA4
SCHEMBL4536065 0.79 CHRNB2 (0.42) HTR2CHTR2BHTR2ACHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
EP-0211746-A1 Phenyl-piperazine derivatives, process for their preparation and therapeutical use LABORATOIRE L. LAFON Société anonyme dite: (FR) 1987-02-25 EP claimed
US-12121868-B2 Doubly porous multi-layer desal membrane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-22 US disclosed
US-12109538-B2 Polysulfone-supported separation membrane KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-08 US disclosed
US-12097473-B2 Crossflow desalination device KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-09-24 US disclosed
US-20240261739-A1 DOUBLY POROUS MULTI-LAYER DESAL MEMBRANE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-08-08 US disclosed
US-20240261738-A1 POLYSULFONE-SUPPORTED SEPARATION MEMBRANE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-08-08 US disclosed
US-20240216872-A1 CROSSFLOW DESALINATION DEVICE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-07-04 US disclosed
US-11969696-B2 Multi-layer membrane containing mixed polyamide selective layer and methods of making thereof KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-04-30 US disclosed
US-20210113971-A1 MULTI-LAYER MEMBRANE CONTAINING MIXED POLYAMIDE SELECTIVE LAYER AND METHODS OF MAKING THEREOF KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2021-04-22 US disclosed
EP-2661435-A1 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS Janssen Pharmaceuticals, Inc. (US) 2013-11-13 EP disclosed
CN-103298809-A 1,2, 4-triazolo [4,3-a ] pyridine derivatives and their use as positive allosteric modulators of MGLUR2 receptors JANSSEN PHARMACEUTICALS INC 2013-09-11 CN disclosed
WO-2013045413-A1 6-(4-HYDROXY-PHENYL)-3-ALKYL-1H-PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS SANOFI (FR) 2013-04-04 WO disclosed
WO-2012062759-A1 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS Janssen Pharmaceuticals, Inc. (US) 2012-05-18 WO disclosed
WO-2012062759-A1 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS Janssen Pharmaceuticals, Inc. (US) 2012-05-18 WO disclosed
US-5053509-A Microbiocides; AIDS LABORATOIRE ROGER BELLON (FR) 1991-10-01 US disclosed
EP-0211746-A1 Phenyl-piperazine derivatives, process for their preparation and therapeutical use LABORATOIRE L. LAFON Société anonyme dite: (FR) 1987-02-25 EP disclosed
EP-0211746-A1 Phenyl-piperazine derivatives, process for their preparation and therapeutical use LABORATOIRE L. LAFON Société anonyme dite: (FR) 1987-02-25 EP disclosed