SCHEMBL453355

SCHEMBL453355

CCCCCCCCOC(=O)CC(c1ccc(O)c(C(C)(C)C)c1)n1nc2ccc(Cl)cc2n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
GAA P10253 1/20 0.37
XBP1 P17861 1/20 0.37
ATM Q13315 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
EPHX2 P34913 4/20 0.33
NR1H4 Q96RI1 1/20 0.33
PSEN1 P49768 2/20 0.33
PSEN2 P49810 2/20 0.33
APH1B Q8WW43 2/20 0.33
NCSTN Q92542 2/20 0.33
APH1A Q96BI3 2/20 0.33
PSENEN Q9NZ42 2/20 0.33
KDM4E B2RXH2 1/20 0.32
KDM4A O75164 1/20 0.32
KDM4C Q9H3R0 1/20 0.32
APP P05067 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16210609 0.90 NPSR1 (0.39) L3MBTL1GAAXBP1ATMNPSR1
SCHEMBL5313580 0.87 ALDH1A1 (0.44) CNR1L3MBTL1GAAXBP1ATM
SCHEMBL3968291 0.85 NR1H4 (0.38) CNR1ALDH1A1NR1H4KMT2A
SCHEMBL135176 0.82 GAA (0.38) CNR1L3MBTL1GAAXBP1ATM
SCHEMBL28729927 0.75 GAA (0.46) L3MBTL1GAAXBP1ATMNPSR1
SCHEMBL5617864 0.75 GAA (0.46) L3MBTL1GAAXBP1ATMNPSR1
SCHEMBL3969785 0.74 TNF (0.41) ALDH1A1TDP1KDM4E
SCHEMBL29603281 0.73 PSEN1 (0.38) CNR1L3MBTL1ALDH1A1TDP1PSEN1
SCHEMBL135175 0.73 PSEN1 (0.38) CNR1L3MBTL1ALDH1A1TDP1PSEN1
SCHEMBL4855821 0.72 EPHX2 (0.37) CNR1L3MBTL1GAAALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO claimed
US-20250136169-A1 THERMOPLASTIC POLYURETHANE FOAM STEERING WHEEL COVER LUBRIZOL ADVANCED MATERIALS, INC. (US) 2025-05-01 US disclosed
US-20250067052-A1 SILICONE MEMBRANES AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2025-02-27 US disclosed
US-20240375701-A1 STEERING WHEEL CONSTRUCTION LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-11-14 US disclosed
WO-2023043779-A1 THERMOPLASTIC POLYURETHANE FOAM STEERING WHEEL COVER LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-03-23 WO disclosed
WO-2023043780-A1 STEERING WHEEL CONSTRUCTION LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-03-23 WO disclosed
US-11525264-B2 Silicone membranes HOLCIM TECHNOLOGY LTD (CH) 2022-12-13 US disclosed
US-20200181911-A1 SILICONE MEMBRANES HOLCIM TECHNOLOGY LTD (CH) 2020-06-11 US disclosed
US-10577801-B2 Silicone membranes FIRESTONE BUILDING PRODUCTS COMPANY, LLC (US) 2020-03-03 US disclosed
US-9896601-B2 Dirt pick-up resistant silicone compositions Gaco Western, LLC (US) 2018-02-20 US disclosed
US-20040178534-A1 Co-injection nozzle, method of its use, and resulting golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-09-16 US disclosed
US-20040176184-A1 Multi-layer golf ball with translucent cover ACUSHNET COMPANY 2004-09-09 US disclosed
US-20040176188-A1 Multi-layer golf ball with translucent cover ACUSHNET COMPANY 2004-09-09 US disclosed
US-20040176531-A1 Multi-layer golf ball with translucent cover JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-09-09 US disclosed
US-20040176185-A1 Multi-layer golf ball with translucent cover ACUSHNET COMPANY 2004-09-09 US disclosed
EP-0752612-B1 Electrochromic device NIPPON MITSUBISHI OIL CORP (JP) 2004-04-21 EP disclosed
US-20040018895-A1 Urethane elastomers with improved color stability JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-01-29 US disclosed
US-20020086743-A1 Urethane elastomers with improved color stability ACUSHNET COMPANY 2002-07-04 US disclosed
US-5859722-A Electrochromic device NIPPOM OIL CO., LTD (JP) 1999-01-12 US disclosed
EP-0752612-A1 Electrochromic device NIPPON OIL CO., LTD. (JP) 1997-01-08 EP disclosed