SCHEMBL453358

SCHEMBL453358

C=CC(=O)OC(=O)C(C)O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.50
ALDH1A1 P00352 6/20 0.39
TP53 P04637 4/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.38
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28190659 0.98 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
Ammonia Solution, Strong SCHEMBL28082936 0.98 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28082825 0.98 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28082930 0.98 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28082964 0.98 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
Biphenyl SCHEMBL28137100 0.84 THRB (0.41) TSHRALDH1A1MAPK1SMN1; SMN2THRB
SCHEMBL2722981 0.83 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9384923 0.80 HCAR2 (0.39) TSHRALDH1A1TP53
SCHEMBL746755 0.80 HCAR2 (0.39) TSHRALDH1A1TP53
Acrylic Acid SCHEMBL28914099 0.80 HCAR2 (0.47) TSHRALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110590554-A Diester acid protection structure monomer and preparation method thereof 宁波南大光电材料有限公司 2019-12-20 CN claimed
CN-110494289-A The method of inkjet printing on rectifier ALIGN TECHNOLOGY INC 2019-11-22 CN claimed
CN-105820050-B A kind of environment-friendly type lactate acrylate monomer and preparation method thereof 苏州吉人高新材料股份有限公司 2018-11-02 CN claimed
CN-107693506-A Magnetic lignin nano-medicament carrier 天津科技大学 2018-02-16 CN claimed
US-9650651-B2 Method for production of n-propanol and other C3-containing products from syngas by symbiotic co-cultures of anaerobic microorganisms SYNATA BIO, INC. 2017-05-16 US claimed
CN-105646202-A Preparation method of UV monomer for paint and UV monomer for paint 苏州吉人高新材料股份有限公司 2016-06-08 CN claimed
WO-2014140335-A1 METHOD FOR PRODUCTION OF N-PROPANOL AND OTHER C3-CONTAINING PRODUCTS FROM SYNGAS BY SYMBIOTIC CO-CULTURES OF ANAEROBIC MICROORGANISMS TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2014-09-18 WO claimed
US-20140273120-A1 Method for production of n-propanol and other C3-containing products from syngas by symbiotic co-cultures of anaerobic microorganisms SYNATA BIO, INC. 2014-09-18 US claimed
EP-1077677-B1 PROCESS FOR THE MANUFACTURE OF A BIOLOGICALLY ACTIVE COMPOSITION JAGOTEC AG (CH) 2003-10-22 EP claimed
WO-2002068527-A2 NOVEL β-OXO COMPOUNDS AND THEIR USE IN PHOTORESIST ARCH SPECIALTY CHEMICALS, INC. (US) 2002-09-06 WO claimed
EP-1077677-A1 BIOLOGICALLY ACTIVE COMPOSITION BIOGLAN AB (SE) 2001-02-28 EP claimed
WO-1999058109-A1 BIOLOGICALLY ACTIVE COMPOSITION BIOGLAN AB (SE) 1999-11-18 WO claimed
CN-118440028-A Water-soluble tetrahydropyrrole lactoyl amide acrylate bio-based monomer and polymer thereof 吉林大学 2024-08-06 CN disclosed
US-11697749-B2 Multilayer adhesive tape KOZA NOVEL MATERIALS KOREA CO., LTD. 2023-07-11 US disclosed
US-20210079269-A1 Multilayer Adhesive Tape LG CHEM, LTD. (KR) 2021-03-18 US disclosed
CN-110590554-A Diester acid protection structure monomer and preparation method thereof 宁波南大光电材料有限公司 2019-12-20 CN disclosed
WO-1999058109-A1 BIOLOGICALLY ACTIVE COMPOSITION BIOGLAN AB (SE) 1999-11-18 WO disclosed
EP-0842209-A2 MULTIBLOCK BIODEGRADABLE HYDROGELS FOR USE AS CONTROLLED RELEASE AGENTS FOR DRUGS AND TISSUE TREATMENT AGENTS FOCAL, INC. (US) 1998-05-20 EP disclosed
WO-1997005185-A2 MULTIBLOCK BIODEGRADABLE HYDROGELS FOR USE AS CONTROLLED RELEASE AGENTS FOR DRUGS DELIVERY AND TISSUE TREATMENT AGENTS FOCAL, INC. (US) 1997-02-13 WO disclosed
US-5478553-A High humidity curl retention NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1995-12-26 US disclosed