SCHEMBL2722981

SCHEMBL2722981

C=CC(=O)OC(=O)C(C)C

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.52
HPGD P15428 1/20 0.40
ALDH1A1 P00352 6/20 0.39
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
THRB P10828 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL453358 0.83 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28082930 0.81 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27442768 0.81 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28190659 0.81 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
Ammonia Solution, Strong SCHEMBL28082936 0.81 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9806301 0.81 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9169902 0.81 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28082825 0.81 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28082964 0.81 TSHR (0.48) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28082776 0.79 TSHR (0.47) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54085294-A None JP disclosed
EP-4267708-B1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS INFINEUM INT LTD (GB) 2025-07-02 EP disclosed
US-12281203-B2 Thermally responsive brush polymers having a copolymer backbone and copolymer arms INFINEUM INTERNATIONAL LIMITED (GB) 2025-04-22 US disclosed
US-20240309155-A1 Thermally Responsive Brush Polymers Having a Copolymer Backbone and Copolymer Arms INFINEUM INTERNATIONAL LIMITED (GB) 2024-09-19 US disclosed
EP-4267708-A1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS Infineum International Limited (GB) 2023-11-01 EP disclosed
WO-2022136384-A1 THERMALLY RESPONSIVE BRUSH POLYMERS HAVING A COPOLYMER BACKBONE AND COPOLYMER ARMS INFINEUM INTERNATIONAL LIMITED (GB) 2022-06-30 WO disclosed
CN-110312768-A Ink-jet ink 惠普发展公司,有限责任合伙企业 2019-10-08 CN disclosed
CN-110198965-A Polyurethane-based adhesive dispersions 惠普发展公司,有限责任合伙企业 2019-09-03 CN disclosed
CN-110177818-A Adhesive dispersion based on polyurethane 惠普发展公司,有限责任合伙企业 2019-08-27 CN disclosed
CN-106199806-B Polarizer and display device comprising it 三星SDI株式会社 2019-08-13 CN disclosed
CN-103320046-A Adhesion enhancing agent, aqueous adhesive agent and adhesive sheet DAINIPPON INK & CHEMICALS 2013-09-25 CN disclosed
US-20130237678-A1 ETHYLENE-BASED POLYMERS AND PROCESSES FOR THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2013-09-12 US disclosed
EP-2632961-A1 ETHYLENE-BASED POLYMERS AND PROCESSES FOR THE SAME Dow Global Technologies LLC (US) 2013-09-04 EP disclosed
CN-103282391-A Ethylene-based polymers and processes for the same DOW GLOBAL TECHNOLOGIES INC 2013-09-04 CN disclosed
US-20120301416-A1 Cosmetic Composition Containing A Polymer Blend ELC MANAGEMENT LLC 2012-11-29 US disclosed
WO-2012057975-A1 ETHYLENE-BASED POLYMERS AND PROCESSES FOR THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2012-05-03 WO disclosed
EP-2185127-A2 COSMETIC COMPOSITIONS CONTAINING A POLYMER BLEND ELC Management LLC (US) 2010-05-19 EP disclosed
WO-2009018064-A2 COSMETIC COMPOSITIONS CONTAINING A POLYMER BLEND ELC MANAGEMENT LLC (US) 2009-02-05 WO disclosed
US-20090035335-A1 Cosmetic Composition Containing a Polymer Blend ELC MANAGEMENT LLC 2009-02-05 US disclosed
JP-S5485294-A PREPARATION OF VINYL CHLORIDE COPOLYMER CHISSO CORP 1979-07-06 JP disclosed