SCHEMBL4533753

SCHEMBL4533753

O=C(O)c1c[nH]cc1-c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.69
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
MAPT P10636 2/20 0.57
HTT P42858 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.56
MAPK1 P28482 1/20 0.56
HNF4A P41235 1/20 0.52
PTPN1 P18031 2/20 0.48
ALOX15 P16050 1/20 0.48
PRKAB2 O43741 2/20 0.47
PRKAG1 P54619 2/20 0.47
PRKAA2 P54646 2/20 0.47
PRKAA1 Q13131 2/20 0.47
PRKAG3 Q9UGI9 2/20 0.47
PRKAG2 Q9UGJ0 2/20 0.47
PRKAB1 Q9Y478 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27634042 0.87 ALDH1A1 (0.81) ALDH1A1KMT2AMEN1MAPTHTT
SCHEMBL319126 0.86 ALDH1A1 (0.58) ALDH1A1KMT2AMEN1MAPTHTT
SCHEMBL10844866 0.83 ALDH1A1 (0.65) ALDH1A1KMT2AMEN1MAPTHTT
SCHEMBL4662482 0.82 ALDH1A1 (0.49) ALDH1A1KMT2AMEN1MAPTHTT
SCHEMBL14705876 0.82 ALDH1A1 (0.49) ALDH1A1KMT2AMEN1MAPTHTT
SCHEMBL10844950 0.82 ALDH1A1 (1.00) ALDH1A1KMT2AMEN1MAPTHTT
SCHEMBL9336033 0.82 ALDH1A1 (0.49) ALDH1A1KMT2AMEN1MAPTHTT
SCHEMBL1520956 0.81 MKNK1 (0.53) ALDH1A1HTTL3MBTL1MAPK1KDM4E
SCHEMBL30575362 0.81 HNF4A (0.50) ALDH1A1KMT2AMEN1MAPTHTT
SCHEMBL973933 0.80 ALDH1A1 (0.61) ALDH1A1KMT2AMEN1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114344291-B Application of 4-phenyl-1H-pyrrole-3-carboxylic acid in preparation of medicine for treating osteoporosis and liposome 中南大学湘雅医院 2023-09-29 CN claimed
CN-114344291-A Application of 4-phenyl-1H-pyrrole-3-carboxylic acid in preparation of medicine for treating osteoporosis and liposome 中南大学湘雅医院 2022-04-15 CN claimed
US-20090014920-A1 POLYMER FILAMENTS MASSEY UNIVERSITY (NZ) 2009-01-15 US claimed
WO-2006001719-A1 POLYMER FILAMENTS MASSEY UNIVERSITY (NZ) 2006-01-05 WO claimed
CN-114344291-B Application of 4-phenyl-1H-pyrrole-3-carboxylic acid in preparation of medicine for treating osteoporosis and liposome 中南大学湘雅医院 2023-09-29 CN disclosed
CN-114344291-B Application of 4-phenyl-1H-pyrrole-3-carboxylic acid in preparation of medicine for treating osteoporosis and liposome 中南大学湘雅医院 2023-09-29 CN disclosed
CN-114344291-B Application of 4-phenyl-1H-pyrrole-3-carboxylic acid in preparation of medicine for treating osteoporosis and liposome 中南大学湘雅医院 2023-09-29 CN disclosed
CN-114344291-A Application of 4-phenyl-1H-pyrrole-3-carboxylic acid in preparation of medicine for treating osteoporosis and liposome 中南大学湘雅医院 2022-04-15 CN disclosed
CN-114344291-A Application of 4-phenyl-1H-pyrrole-3-carboxylic acid in preparation of medicine for treating osteoporosis and liposome 中南大学湘雅医院 2022-04-15 CN disclosed
CN-114344291-A Application of 4-phenyl-1H-pyrrole-3-carboxylic acid in preparation of medicine for treating osteoporosis and liposome 中南大学湘雅医院 2022-04-15 CN disclosed
CN-105283451-A Novel viral replication inhibitors UNIV LEUVEN KATH 2016-01-27 CN disclosed
US-20090014920-A1 POLYMER FILAMENTS MASSEY UNIVERSITY (NZ) 2009-01-15 US disclosed
EP-1107758-A2 USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE SCIOS INC. (US) 2001-06-20 EP disclosed
WO-2000012074-A2 USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE SCIOS INC. (US) 2000-03-09 WO disclosed
EP-0332704-B1 PROCESS FOR PRODUCING CONDUCTIVE POLYMER FILM NIPPON SODA CO (JP) 1994-12-21 EP disclosed
US-5306443-A Dissolving monomer with metal containing oxidizing agent in sufficient solvent to prevent polymerization; removal of solvent NIPPON SODA CO., LTD. (JP) 1994-04-26 US disclosed
EP-0231394-B1 NOVEL POLYMERS OF3,4-SUBSTITUTED PYRROLE COMPOUND AND PROCESSFOR THEIR PREPARATION NIPPON SODA CO., LTD. (JP) 1991-03-13 EP disclosed
EP-0332704-A1 PROCESS FOR PRODUCING CONDUCTIVE POLYMER FILM NIPPON SODA CO., LTD. (JP) 1989-09-20 EP disclosed
US-4816536-A ELECTROCHROMISM ELEMENTS NIPPON SODA CO., LTD. (JP) 1989-03-28 US disclosed
EP-0231394-A1 NOVEL POLYMERS OF3,4-SUBSTITUTED PYRROLE COMPOUND AND PROCESSFOR THEIR PREPARATION NIPPON SODA CO., LTD. (JP) 1987-08-12 EP disclosed