SCHEMBL453448

SCHEMBL453448

CC(=O)Nc1ccn([C@@H]2O[C@H](CO)C(O)C2O)c(=O)n1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.65
MTOR P42345 2/20 0.65
THRB P10828 1/20 0.65
MDM2 Q00987 1/20 0.65
NCOA1 Q15788 1/20 0.65
NCOA3 Q9Y6Q9 1/20 0.65
MAPT P10636 1/20 0.55
CDA P32320 1/20 0.55
ALDH1A1 P00352 2/20 0.52
GMNN O75496 1/20 0.52
TP53 P04637 1/20 0.52
NFKB1 P19838 1/20 0.52
DNMT1 P26358 1/20 0.52
THPO P40225 1/20 0.52
HTT P42858 1/20 0.52
RAB9A P51151 1/20 0.52
BLM P54132 1/20 0.52
HBB P68871 1/20 0.52
PMP22 Q01453 1/20 0.52
SLC28A1 O00337 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20967857 1.00 LMNA (0.65) LMNAMTORTHRBMDM2NCOA1
SCHEMBL20628772 1.00 LMNA (0.65) LMNAMTORTHRBMDM2NCOA1
SCHEMBL14946394 1.00 LMNA (0.65) LMNAMTORTHRBMDM2NCOA1
SCHEMBL20459954 1.00 LMNA (0.65) LMNAMTORTHRBMDM2NCOA1
SCHEMBL6397305 1.00 LMNA (0.65) LMNAMTORTHRBMDM2NCOA1
SCHEMBL14929347 1.00 LMNA (0.65) LMNAMTORTHRBMDM2NCOA1
SCHEMBL453447 1.00 LMNA (0.65) LMNAMTORTHRBMDM2NCOA1
Phosphoric Acid SCHEMBL15668496 0.96 LMNA (0.60) LMNAMTORTHRBMDM2NCOA1
Cytidine SCHEMBL15054404 0.94 LMNA (0.77) LMNAMTORTHRBMDM2NCOA1
SCHEMBL27056643 0.92 LMNA (0.55) LMNAMTORTHRBMDM2NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5333 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026103936-A1 CHEMICALLY MODIFIED CIRCULAR RNA MOLECULE, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海元码智药生物技术有限公司 2026-05-21 WO claimed
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 US claimed
US-12618064-B2 Acetylated ribonucleic acids and uses thereof HELIX NANOTECHNOLOGIES INC (US) 2026-05-05 US claimed
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
US-20260078413-A1 METHODS AND PRODUCTS FOR EXPRESSING PROTEINS IN CELLS FACTOR BIOSCIENCE INC (US) 2026-03-19 US claimed
US-20260071215-A1 SYSTEMS FOR ENHANCING TARGET MRNA EXPRESSION AND USES THEREOF UNIV JOHNS HOPKINS (US) 2026-03-12 US claimed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 EP claimed
EP-4705468-A1 MAMMALIAN POLYCISTRONIC EXPRESSION SYSTEM FOR DIRECT TRANSLATION FROM RNA AND SECRETION OF CARGO California Institute of Technology (US) 2026-03-11 EP claimed
US-12551551-B2 Compositions comprising α-factor prepro sequence and uses thereof HELIX NANOTECHNOLOGIES INC (US) 2026-02-17 US claimed
US-20260034204-A1 RNA ENCODING VIRUS-LIKE PARTICLES AND USES THEREOF SEQIRUS INC (US) 2026-02-05 US claimed
CN-1297565-C Method for preparing 2',3'2-dideoxycytidine LU JINKANG (CN) 2007-01-31 CN claimed
CN-1563030-A Method for preparing 2',3'2-dideoxycytidine LU JINKANG (CN) 2005-01-12 CN claimed
US-20040110718-A1 Anti-HCV nucleoside derivatives DEVOS RENE (GB) 2004-06-10 US claimed
CN-1466591-A Nucleoside derivatives - 2004-01-07 CN claimed
WO-2002018404-A9 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C HOFFMANN LA ROCHE (CH) 2003-10-02 WO claimed
EP-1315736-A2 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C F. HOFFMANN-LA ROCHE AG (CH) 2003-06-04 EP claimed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
US-20030008841-A1 Anti-HCV nucleoside derivatives F. HOFFMAN-LA ROCHE, A SWISS COMPANY (CH) 2003-01-09 US claimed
US-6365374-B1 NUCLEOTIDE STABILIZES RIBOZYMES AND ANTISENSE OLIGONUCLEOTIDES RIBOZYME PHARMACEUTICALS, INC. 2002-04-02 US claimed
WO-2002018404-A2 NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF HEPATITIS C F. HOFFMANN-LA ROCHE AG (CH) 2002-03-07 WO claimed