SCHEMBL453471

SCHEMBL453471

Nc1ccc(C(=O)O)c(CCc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.50
MAOA P21397 4/20 0.50
MAPT P10636 4/20 0.49
ALDH1A1 P00352 4/20 0.49
CYP3A4 P08684 2/20 0.49
KDM4E B2RXH2 2/20 0.49
GAA P10253 1/20 0.49
ESR2 Q92731 1/20 0.49
PTPN1 P18031 1/20 0.49
MCL1 Q07820 2/20 0.47
BCL2A1 Q16548 1/20 0.47
MEN1 O00255 2/20 0.44
THRB P10828 2/20 0.44
RECQL P46063 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
USP2 O75604 1/20 0.44
POLB P06746 1/20 0.44
PKM P14618 1/20 0.44
APEX1 P27695 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28062236 0.89 ALDH1A1 (0.59) MAPTALDH1A1CYP3A4KDM4EGAA
SCHEMBL6384285 0.87 MAOB (0.50) MAOBMAOAMAPTALDH1A1CYP3A4
SCHEMBL2146135 0.85 PTPN1 (0.53) MAPTALDH1A1CYP3A4KDM4EGAA
SCHEMBL6024151 0.84 TSHR (0.41) MAPTALDH1A1CYP3A4KDM4EGAA
SCHEMBL19511210 0.84 MAPT (0.54) MAPTALDH1A1CYP3A4KDM4EGAA
SCHEMBL11598778 0.83 TSHR (0.53) ALDH1A1KDM4EGAAHSD17B10ADRB2
SCHEMBL29632227 0.82 ALDH1A1 (0.55) MAPTALDH1A1CYP3A4KDM4EGAA
SCHEMBL29632107 0.82 ALDH1A1 (0.55) MAPTALDH1A1CYP3A4KDM4EGAA
SCHEMBL308882 0.82 ALDH1A1 (0.55) MAPTALDH1A1CYP3A4KDM4EGAA
SCHEMBL343331 0.82 ALDH1A1 (0.55) MAPTALDH1A1CYP3A4KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095128-B1 AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT PROCTER & GAMBLE (US) 2005-04-20 EP claimed
US-20050009727-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2005-01-13 US claimed
US-20040116320-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2004-06-17 US claimed
US-20030211963-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY 2003-11-13 US claimed
US-6566312-B2 A softener comprising a perfume which imparts a fresh fragrance to laundered fabrics and is long-lasting; reaction product of primary and or secondary amines and a ketone or aldehyde; time release agents PROCTER & GAMBLE COMPANY 2003-05-20 US claimed
US-20030064899-A1 Amine reaction compounds comprising one or more active ingredient THE PROCTER & GAMBLE COMPANY 2003-04-03 US claimed
CN-1335883-A Laundry and Cleaning Compositions PROCTER & GAMBLE (US) 2002-02-13 CN claimed
EP-1144566-A2 LAUNDRY AND CLEANING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-10-17 EP claimed
EP-1095128-A1 AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT THE PROCTER & GAMBLE COMPANY (US) 2001-05-02 EP claimed
WO-2000002991-A1 AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT THE PROCTER & GAMBLE COMPANY (US) 2000-01-20 WO claimed
WO-2000002981-A2 LAUNDRY AND CLEANING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-01-20 WO claimed
EP-0971024-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP claimed
EP-0971025-A1 Amine reaction compounds comprising one or more active ingredient THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP claimed
US-20240206461-A1 DELIVERY PARTICLES WITH HIGH CORE:WALL RATIOS ENCAPSYS, LLC (US) 2024-06-27 US disclosed
US-12016963-B2 Freshening compositions with alkoxylated phenols THE PROCTER & GAMBLE COMPANY (US) 2024-06-25 US disclosed
EP-4370644-A1 CONSUMER PRODUCTS COMPRISING DELIVERY PARTICLES WITH HIGH CORE:WALL RATIOS The Procter & Gamble Company (US) 2024-05-22 EP disclosed
WO-2000002991-A1 AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT THE PROCTER & GAMBLE COMPANY (US) 2000-01-20 WO disclosed
EP-0971024-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP disclosed
EP-0971025-A1 Amine reaction compounds comprising one or more active ingredient THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP disclosed
EP-0971021-A1 Process for producing particles of amine reaction product THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240206461-A1 DELIVERY PARTICLES WITH HIGH CORE:WALL RATIOS CETP, CHMP4B, HDLBP MAOB 2122/4885MAOA 1428/4885MAPT 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.