SCHEMBL6024151

SCHEMBL6024151

CC(CCc1ccccc1)CCc1cc(N)ccc1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPT P10636 2/20 0.41
CYP3A4 P08684 2/20 0.41
GAA P10253 1/20 0.41
ESR2 Q92731 1/20 0.41
KDM4E B2RXH2 1/20 0.41
PTPN1 P18031 1/20 0.41
KMT2A Q03164 4/20 0.40
MCL1 Q07820 1/20 0.40
BCL2A1 Q16548 1/20 0.40
MEN1 O00255 3/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HPGD P15428 1/20 0.40
POLB P06746 2/20 0.39
FOLH1 Q04609 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL453471 0.84 MAOB (0.50) ALDH1A1MAPTCYP3A4GAAESR2
SCHEMBL6024229 0.84 MAPT (0.41) ALDH1A1MAPTCYP3A4GAAESR2
SCHEMBL6024055 0.82 ALOX15 (0.40) ALDH1A1MAPTCYP3A4GAAESR2
SCHEMBL6024546 0.81 ALDH1A1 (0.41) ALDH1A1MAPTCYP3A4GAAESR2
SCHEMBL7761965 0.81 MAPT (0.49) ALDH1A1MAPTCYP3A4GAAESR2
SCHEMBL28062236 0.77 ALDH1A1 (0.59) ALDH1A1MAPTCYP3A4GAAESR2
SCHEMBL2146135 0.76 PTPN1 (0.53) TSHRALDH1A1MAPTCYP3A4GAA
SCHEMBL8405167 0.76 ALDH1A1 (0.50) ALDH1A1MAPTCYP3A4GAAESR2
SCHEMBL17881330 0.76 ALDH1A1 (0.41) ALDH1A1MAPTCYP3A4GAAESR2
SCHEMBL19511210 0.76 MAPT (0.54) ALDH1A1MAPTCYP3A4GAAESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7129204-B2 Perfumes QUEST INTERNATIONAL SERVICES B.V. (NL) 2006-10-31 US disclosed
EP-1286651-B1 USE OF AMINOBENZOIC ACIDS IN COMPOSITIONS WITH PERFUMES QUEST INT SERV BV (NL) 2006-08-02 EP disclosed
US-20030199422-A1 Perfumes QUEST INTERNATIONAL SERVICES B.V. (NL) 2003-10-23 US disclosed
EP-1286651-A1 IMPROVEMENTS IN OR RELATING TO PERFUMES QUEST INTERNATIONAL NEDERLAND BV (NL) 2003-03-05 EP disclosed
WO-2001093823-A1 IMPROVEMENTS IN OR RELATING TO PERFUMES QUEST INTERNATIONAL B.V. (NL) 2001-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199422-A1 Perfumes PAH, PIR, TRPA1 TSHR 3394/4885ALDH1A1 679/4885MAPT 1098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.