SCHEMBL453503

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL449608	0.88	GSTO1 (0.58)	GSTO1GAAMAPTTHRBPIK3CD
	SCHEMBL439443	0.81	CYP2C19 (0.51)	GSTO1GAA
	SCHEMBL3717918	0.80	GAA (0.67)	GSTO1GAAMAPTPIK3CDPIK3CG
	SCHEMBL30794423	0.79	GSTO1 (0.44)	GSTO1GAAMAPTTHRBPDK1
	SCHEMBL439442	0.79	GSTO1 (0.44)	GSTO1GAAMAPTTHRBPDK1
	SCHEMBL9321470	0.75	GSTO1 (0.60)	GSTO1GAATHRBPIK3CDPIK3CG
	SCHEMBL9321467	0.75	GSTO1 (0.60)	GSTO1GAAPIK3CDPIK3CGPI4KB
	SCHEMBL30516775	0.75	GSTO1 (0.60)	GSTO1GAATHRBPIK3CDPIK3CG
	SCHEMBL438018	0.74	TOP2A (0.38)	GSTO1
	SCHEMBL448977	0.71	CYP2C19 (0.46)	GSTO1GAAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.