SCHEMBL30100550

SCHEMBL30100550

[2H]n1cnc2c(C(=O)O)cccc21

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.54
KDM4E B2RXH2 2/20 0.45
HPGD P15428 1/20 0.45
DHODH Q02127 8/20 0.44
ALDH1A1 P00352 2/20 0.42
NAPRT Q6XQN6 1/20 0.42
TDP1 Q9NUW8 1/20 0.39
ALOX15 P16050 1/20 0.39
KEAP1 Q14145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL453514 0.86 PARP1 (0.72) PARP1KDM4EHPGDDHODHALDH1A1
Hydrochloric Acid SCHEMBL2129546 0.84 PARP1 (0.70) PARP1KDM4EHPGDDHODHALDH1A1
Hydrochloric Acid SCHEMBL22165594 0.84 PARP1 (0.70) PARP1KDM4EHPGDDHODHALDH1A1
SCHEMBL28284556 0.84 PARP1 (0.70) PARP1KDM4EHPGDDHODHALDH1A1
SCHEMBL9218238 0.84 PARP1 (0.70) PARP1KDM4EHPGDDHODHALDH1A1
Acetic Acid SCHEMBL7575146 0.81 PARP1 (0.66) PARP1KDM4EHPGDDHODH
Trifluoroacetic Acid SCHEMBL20482044 0.78 PARP1 (0.60) PARP1KDM4EHPGDDHODH
SCHEMBL28267894 0.75 PARP1 (0.61) PARP1KDM4EHPGD
Tromethamine SCHEMBL16115019 0.74 PARP1 (0.60) PARP1KDM4EHPGD
SCHEMBL30448349 0.72 ALDH1A1 (0.42) KDM4EDHODHALDH1A1NAPRTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115403567-A Recovery method of candesartan cilexetil mother liquor 珠海润都制药股份有限公司 2022-11-29 CN disclosed