Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526497 | 0.93 | MCHR1 (0.57) | MCHR1 | |
| SCHEMBL4526681 | 0.88 | MCHR1 (0.50) | MCHR1KDM4C | |
| SCHEMBL1003466 | 0.87 | MCHR1 (0.52) | MCHR1KDM4CNPC1RAB9AP2RX3 | |
| SCHEMBL4533300 | 0.86 | MCHR1 (0.54) | MCHR1KDM4CL3MBTL1 | |
| SCHEMBL1001633 | 0.84 | MCHR1 (0.51) | MCHR1KDM4CP2RX3 | |
| SCHEMBL4532713 | 0.84 | KDM4C (0.44) | MCHR1KDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL5267094 | 0.81 | MCHR1 (0.56) | MCHR1 | |
| SCHEMBL4537303 | 0.81 | MCHR1 (0.59) | MCHR1 | |
| SCHEMBL4534608 | 0.81 | MCHR1 (0.59) | MCHR1 | |
| SCHEMBL4532738 | 0.81 | MCHR1 (0.59) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | MSD K.K. (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1939194-A1 | BICYCLIC AROMATIC SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | PYCR1, CHRM1, MTR | MCHR1 357/4885KDM4C 1474/4885NPC1 3130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.