Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.60 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | IL2 | P60568 | 1/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453543 | 1.00 | CA2 (0.60) | CA2CA1CA12CA9LNPEP | |
| SCHEMBL8297896 | 0.90 | CA2 (0.53) | CA2CA1CA12CA9LNPEP | |
| SCHEMBL8588574 | 0.90 | CA2 (0.59) | CA2CA1ACEPTPN1ALOX5 | |
| SCHEMBL7971423 | 0.90 | CA2 (0.59) | CA2CA1ACEPTPN1ALOX5 | |
| SCHEMBL6938746 | 0.90 | CA2 (0.59) | CA2CA1ACEPTPN1ALOX5 | |
| SCHEMBL6850655 | 0.90 | CA2 (0.59) | CA2CA1ACEPTPN1ALOX5 | |
| SCHEMBL11121735 | 0.83 | CA1 (0.64) | CA2CA1CA12CA9LNPEP | |
| SCHEMBL7510215 | 0.82 | CA2 (0.59) | CA2CA1ITGB3ITGA2BACE | |
| SCHEMBL8104529 | 0.82 | CA2 (0.59) | CA2CA1ITGB3ITGA2BACE | |
| SCHEMBL4364568 | 0.82 | CA2 (0.65) | CA2CA1CA12CA9ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | claimed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | claimed |
| US-20120064601-A1 | Chromatography Membranes for the Purification of Chiral Compounds | NATRIX SEPARATIONS INC. (CA) | 2012-03-15 | — | — | US | claimed |
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | disclosed |
| US-20120064601-A1 | Chromatography Membranes for the Purification of Chiral Compounds | NATRIX SEPARATIONS INC. (CA) | 2012-03-15 | — | — | US | disclosed |
| US-7064234-B2 | Enantioselective cation-exchange materials | CHIRAL TECHNOLOGIES EUROPE SAS (FR) | 2006-06-20 | — | — | US | disclosed |
| EP-1474234-B1 | ENANTIOSELECTIVE CATION-EXCHANGE MATERIALS | LINDNER WOLFGANG PROF DR (AT) | 2005-07-20 | — | — | EP | disclosed |
| US-20050131087-A1 | Enantioselective cation-exchange materials | CHIRAL TECHNOLOGIES EUROPE SAS (FR) | 2005-06-16 | — | — | US | disclosed |
| EP-1474234-A1 | ENANTIOSELECTIVE CATION-EXCHANGE MATERIALS | Lindner, Wolfgang, Prof. Dr. (AT) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068397-A1 | ENANTIOSELECTIVE CATION-EXCHANGE MATERIALS | LINDNER WOLFGANG (AT) | 2003-08-21 | — | — | WO | disclosed |