Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104529 | 1.00 | CA2 (0.59) | CA2ACENPC1TP53RAB9A | |
| SCHEMBL6850655 | 0.90 | CA2 (0.59) | CA2ACENPC1TP53RAB9A | |
| SCHEMBL8588574 | 0.90 | CA2 (0.59) | CA2ACENPC1TP53RAB9A | |
| SCHEMBL6938746 | 0.90 | CA2 (0.59) | CA2ACENPC1TP53RAB9A | |
| SCHEMBL7971423 | 0.90 | CA2 (0.59) | CA2ACENPC1TP53RAB9A | |
| SCHEMBL7442014 | 0.85 | CA2 (0.74) | CA2ACENPC1TP53RAB9A | |
| SCHEMBL7442005 | 0.85 | CA2 (0.74) | CA2ACENPC1TP53RAB9A | |
| SCHEMBL4366751 | 0.83 | CA2 (0.67) | CA2ACENPC1TP53RAB9A | |
| SCHEMBL27659000 | 0.83 | CA2 (0.67) | CA2ACENPC1TP53RAB9A | |
| SCHEMBL453542 | 0.82 | CA2 (0.60) | CA2ACECA1PTPN1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948483-B1 | FARNESYL TRANSFERASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2002-03-13 | — | — | EP | disclosed |
| EP-0948483-A1 | FARNESYL TRANSFERASE INHIBITORS | Aventis Pharma S.A. (FR) | 1999-10-13 | — | — | EP | disclosed |
| EP-0839133-B1 | 4,9-ETHANO-BENZO(F)ISOINDOLE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | RHONE POULENC RORER SA (FR) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998029390-A1 | FARNESYL TRANSFERASE INHIBITORS | RHONE-POULENC RORER S.A. (FR) | 1998-07-09 | — | — | WO | disclosed |
| EP-0839133-A1 | 4,9-ETHANO-BENZO(F)ISOINDOLE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | Aventis Pharma S.A. (FR) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003050-A1 | 4,9-ETHANO-BENZO(F)ISOINDOLE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | RHONE-POULENC RORER S.A. (FR) | 1997-01-30 | — | — | WO | disclosed |