Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL7779839 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL51070 | 1.00 | — | — | |
| Pyridine SCHEMBL51069 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL839151 | 1.00 | — | — | |
| Pyridine SCHEMBL7628539 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL3113408 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL839150 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL18059958 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL11442039 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL26624876 | 1.00 | TSHR (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8182 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060012-A | Preparation method of eplerenone and intermediate thereof | 江西百思康瑞药业有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122010996-A | Preparation method and application of dual-response fluorescent probe for detecting polarity and peroxynitrite | 郑州大学 | 2026-05-12 | — | — | CN | claimed |
| US-20260070871-A1 | PROCESS FOR PREPARATION OF 2-CHLORO-3-FLUORO-4-ALKOXY-ANILINES AND 2-FLUORO-3-CHLOROPHENOL | BAYER AG (DE) | 2026-03-12 | — | — | US | claimed |
| EP-4656639-A1 | METHOD FOR THE PREPARATION OF IBOGAMINE AND PURIFICATION OF IBOGAMINE AND IBOGAMINE-TYPE COMPOUNDS | Oeri, Hans (CA) | 2025-12-03 | — | — | EP | claimed |
| WO-2025245379-A1 | SUPERCRITICAL FLUIDS REGENERATION OF PFAS-CONTAMINATED SPENT MEDIA AND WATER TREATMENT TRAIN | UNIVERSITY OF WASHINGTON (US) | 2025-11-27 | — | — | WO | claimed |
| US-20250332272-A1 | PREPARATION METHOD FOR DRUG LINKER CONJUGATE AND INTERMEDIATE THEREOF | MEDILINK THERAPEUTICS SUZHOU CO LTD (CN) | 2025-10-30 | — | — | US | claimed |
| WO-2025133718-A1 | AN EFFICIENT PROCESS FOR THE SYNTHESIS OF PARAXANTHINE | FERTIS INDIA PVT. LTD. (IN) | 2025-06-26 | — | — | WO | claimed |
| US-20250171409-A1 | PROCESS OF PREPARATION OF INDOXACARB AND ITS INTERMEDIATES | ADAMA MAKHTESHIM LTD. (IL) | 2025-05-29 | — | — | US | claimed |
| CN-119978236-A | Method for preparing coumarone resin by using ionic liquid catalyst | 宝武碳业科技股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-113121630-B | Progesterone preparation method | 天津药业研究院股份有限公司 | 2025-05-09 | — | — | CN | claimed |
| US-4192802-A | Process for the manufacture of steroid carboxylic acid lactones | CIBA-GEIGY CORPORATION (US) | 1980-03-11 | — | — | US | claimed |
| US-4172960-A | ETHERIFICATION, DEETHERIFICATION, DIALKYLATION | FISONS LIMITED (GB) | 1979-10-30 | — | — | US | claimed |
| US-4147842-A | PYRIDINIUM BROMIDE-BROMINE CHARGE TRANSFER COMPLEX CATHODE | ELEANOR & WILSON GREATBATCH FOUNDATION (US) | 1979-04-03 | — | — | US | claimed |
| US-4127610-A | REMOVAL OF NITROSAMINES | ELI LILLY AND COMPANY (US) | 1978-11-28 | — | — | US | claimed |
| US-4098779-A | Process for the purification and manufacture of secretin | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | claimed |
| US-4039563-A | Process for preparing cyclopent-2-en-1-one derivatives | TEIJIN LIMITED (JA) | 1977-08-02 | — | — | US | claimed |
| US-4025523-A | SOURCES OF HIGHLY PURE SALTS | THE DOW CHEMICAL COMPANY (US) | 1977-05-24 | — | — | US | claimed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | claimed |
| US-3956349-A | TRIETHYL ORTHOACETATE, ACID CATALYST | SYNTEX (U.S.A.) INC. (US) | 1976-05-11 | — | — | US | claimed |
| US-3947570-A | MOUTHWASH, LEMON OIL | COLGATE-PALMOLIVE COMPANY (US) | 1976-03-30 | — | — | US | claimed |