Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL7779839 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL51069 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL839151 | 1.00 | — | — | |
| Pyridine SCHEMBL7628539 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL3113408 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL839150 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL45360 | 1.00 | — | — | |
| Pyridine SCHEMBL18059958 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL11442039 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL26624876 | 1.00 | TSHR (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4369 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059801-A | Synthesis method of Marbalol Sha Wei side chain intermediate | 重庆圣华曦药业股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122036756-A | Flavanone thiazole derivative and preparation method and application thereof | 南通大学 | 2026-05-15 | — | — | CN | claimed |
| CN-121394608-B | Electrolyte for four-electron conversion reaction of water-based zinc-iodine battery | 广东工业大学 | 2026-05-12 | — | — | CN | claimed |
| CN-122010777-A | Method for synthesizing cyclopentane compounds by utilizing bromide ions/visible light synergistic catalysis | 南京工业大学 | 2026-05-12 | — | — | CN | claimed |
| CN-117362284-B | Flumioxazin and its preparation method Process for the preparation of amines | 厦门大学 | 2026-05-12 | — | — | CN | claimed |
| US-20260083721-A1 | 7-CYANO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | JIANGSU YAHONG MEDITECH CO LTD (CN) | 2026-03-26 | — | — | US | claimed |
| EP-4613745-A2 | PROCESS FOR PREPARING A COT INHIBITOR COMPOUND | Gilead Sciences, Inc. (US) | 2025-09-10 | — | — | EP | claimed |
| US-20250248296-A1 | DEFECT ENGINEERING IN WIDE BANDGAP PEROVSKITES FOR EFFICIENT AND STABLE FULLY TEXTURED PEROVSKITE-SILICON TANDEM SOLAR CELLS | UNITED STATES DEPARTMENT OF ENERGY | 2025-07-31 | — | — | US | claimed |
| CN-114507231-B | Lactam compound and preparation method thereof | 南京再明医药有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-120040333-A | Preparation method of 5, 6-dihydroxyindoline | 北京成宇化工有限公司 | 2025-05-27 | — | — | CN | claimed |
| EP-1257527-A1 | (2S)-AMINOINDAN DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-11-20 | — | — | EP | claimed |
| US-20020151596-A1 | Novel process to prepare 2-aminoindan derivatives | ROMERO ARTHUR GLENN (US) | 2002-10-17 | — | — | US | claimed |
| US-6410787-B2 | HYDROGENATION OF RACEMIC 6-ALKOXY-1H-INDENE-1,2(3H)-DIONE-2-OXIME, WITH CHIRAL ACID, RESOLUTION, ALKYLATION, BROMINATION, CARBOXAMIDATION | PHARMACIA & UPJOHN COMPANY | 2002-06-25 | — | — | US | claimed |
| US-6376717-B2 | HALOGENATION OF ZEARANTHIN | PRODEMEX, S.A. DE C.V. (MX) | 2002-04-23 | — | — | US | claimed |
| WO-2002000639-A1 | SYNTHESIS OF CYCLIC COMPOUNDS | UNISEARCH LIMITED (AU) | 2002-01-03 | — | — | WO | claimed |
| US-20010051357-A1 | Preparation of astaxanthin | DSM IP ASSETS B.V. (NL) | 2001-12-13 | — | — | US | claimed |
| US-20010044471-A1 | Novel process to prepare 2-aminoindan derivatives | PHARMACIA & UPJOHN COMPANY | 2001-11-22 | — | — | US | claimed |
| WO-2001081301-A2 | PREPARATION OF ASTAXANTHIN | PRODEMEX, S.A. DE C.V. (MX) | 2001-11-01 | — | — | WO | claimed |
| WO-2001062712-A1 | (2S)-AMINOINDAN DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2001-08-30 | — | — | WO | claimed |
| CN-1069734-A | 11.19-the synthetic method of cyclopolymerized pregnenone analogue | SHANGHAI INST OF FAMILY PLANNI (CN) | 1993-03-10 | — | — | CN | claimed |