Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL7779839 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL51070 | 1.00 | — | — | |
| Pyridine SCHEMBL51069 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL7628539 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL3113408 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL839150 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL45360 | 1.00 | — | — | |
| Pyridine SCHEMBL18059958 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL11442039 | 1.00 | TSHR (0.90) | — | |
| Pyridine SCHEMBL26624876 | 1.00 | TSHR (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072513-B | Preparation method of hepatitis drug intermediate | 苏州敬业医药化工有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-111072513-A | Preparation method of hepatitis drug intermediate | 苏州敬业医药化工有限公司 | 2020-04-28 | — | — | CN | claimed |
| CN-107325143-B | Fulvestrant intermediate synthetic method | 连云港恒运药业有限公司 | 2019-09-10 | — | — | CN | claimed |
| CN-109810047-A | (R) synthetic method of the chiral intermediate of -3- Phenylpiperidine or/and (S) -3- Phenylpiperidine and Ni Lapani | 上海博邦医药科技有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-109485566-A | A kind of novel synthesis of oxo phenylacetate | 宁波江润化工有限公司 | 2019-03-19 | — | — | CN | claimed |
| CN-108358761-A | A kind of salviandic acid A intermediate and preparation method thereof | 上海交通大学 | 2018-08-03 | — | — | CN | claimed |
| US-10022462-B2 | Methods and apparatus for synthesizing imaging agents, and intermediates thereof | LANTHEUS MEDICAL IMAGING, INC. (US) | 2018-07-17 | — | — | US | claimed |
| CN-108251381-A | A kind of paraquat monoclonal antibody hybridoma cell strain and its application | 江南大学 | 2018-07-06 | — | — | CN | claimed |
| CN-108203404-A | (R) synthetic method of -3- Phenylpiperidines or/and the chiral intermediate of (S) -3- Phenylpiperidines and Ni Lapani | 上海博邦医药科技有限公司 | 2018-06-26 | — | — | CN | claimed |
| CN-107325143-A | Fulvestrant intermediate synthetic method | 连云港恒运药业有限公司 | 2017-11-07 | — | — | CN | claimed |
| EP-2534136-A2 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | Lantheus Medical Imaging, Inc. (US) | 2012-12-19 | — | — | EP | claimed |
| CN-102633876-A | Synthetic method and application of paraquat antigen | UNIV JIANGNAN | 2012-08-15 | — | — | CN | claimed |
| CN-101918618-B | Pyrophosphate-based bath for plating on tin alloy layers | ATOTECH DEUTSCHLAND GMBH (DE) | 2012-02-22 | — | — | CN | claimed |
| WO-2011097649-A2 | METHODS AND APPARATUS FOR SYNTHESIZING IMAGING AGENTS, AND INTERMEDIATES THEREOF | LANTHEUS MEDICAL IMAGING, INC. (US) | 2011-08-11 | — | — | WO | claimed |
| CN-101918618-A | Pyrophosphate-based bath for plating on tin alloy layers | ATOTECH DEUTSCHLAND GMBH | 2010-12-15 | — | — | CN | claimed |
| WO-2007133614-A2 | BIS-QUATERNARY AMMONIUM CYCLOPHANE COMPOUNDS THAT INTERACT WITH NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS | UNIVERSITY OF KENTUCKY (US) | 2007-11-22 | — | — | WO | claimed |
| CN-1796371-A | Dicationic bis-hydrazone compound, dye composition comprising at least one such compound, implementation process therefor and uses thereof | OREAL (FR) | 2006-07-05 | — | — | CN | claimed |
| CN-1259316-C | Heterocyclic compounds for age-related and diabetic vascular system complications | TORRENTAU PHARMACEUTICAL LTD (IN) | 2006-06-14 | — | — | CN | claimed |
| CN-1498217-A | Heterocyclic compounds for aging-related and diabetic vascular complications | ������˹ҩƷ��˾ | 2004-05-19 | — | — | CN | claimed |
| CN-85106125-A | Prepare solid-state, the method for the quaternary dipyridinylium salt complex of weeding | — | 1986-07-02 | — | — | CN | claimed |