Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18158039 | 0.80 | ALDH1A1 (0.56) | KDM4EMAPTPOLBTDP1ALDH1A1 | |
| SCHEMBL4249310 | 0.75 | ALDH1A1 (0.50) | KDM4EMAPTPOLBTDP1ALDH1A1 | |
| SCHEMBL18906022 | 0.75 | MAPT (0.58) | KDM4EMAPTPOLBTDP1ALDH1A1 | |
| SCHEMBL9768097 | 0.75 | KDM4E (0.48) | KDM4EMAPTPOLBTDP1ALDH1A1 | |
| SCHEMBL14342240 | 0.73 | ALDH1A1 (0.42) | MAPTALDH1A1SMN1; SMN2TP53KMT2A | |
| SCHEMBL15240 | 0.73 | ALDH1A1 (0.72) | KDM4EMAPTPOLBTDP1ALDH1A1 | |
| SCHEMBL29698615 | 0.73 | MYC (0.49) | KDM4EMAPTPOLBTDP1ALDH1A1 | |
| Phthalic Acid SCHEMBL25407447 | 0.71 | ALDH1A1 (0.69) | KDM4EMAPTPOLBTDP1ALDH1A1 | |
| Water SCHEMBL11574791 | 0.71 | ALDH1A1 (0.69) | KDM4EMAPTPOLBTDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4523562 | 0.71 | ALDH1A1 (0.41) | MAPTTDP1ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150328329-A1 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | American University of Cairo (EG) | 2015-11-19 | — | — | US | disclosed |
| WO-2014081856-A2 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | AZZAZY HASSAN (EG) | 2014-05-30 | — | — | WO | disclosed |
| WO-2012033878-A2 | COMPOUNDS AND METHODS FOR ACEMIF INHIBITION AND THE TREATMENT OF PARASITES | YALE UNIVERSITY (US) | 2012-03-15 | — | — | WO | disclosed |