Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 14/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28275014 | 0.82 | SMN1; SMN2 (0.41) | KDM4EPOLBMAPTTDP1SMN1; SMN2 | |
| SCHEMBL453627 | 0.75 | KDM4E (0.53) | KDM4EPOLBMAPTTDP1SMN1; SMN2 | |
| SCHEMBL28358580 | 0.74 | ALDH1A1 (0.46) | KDM4EPOLBMAPTTDP1SMN1; SMN2 | |
| SCHEMBL9767880 | 0.72 | HTT (0.43) | KDM4EPOLBMAPTTDP1SMN1; SMN2 | |
| SCHEMBL27544152 | 0.71 | KDM4E (0.56) | KDM4EPOLBMAPTTDP1SMN1; SMN2 | |
| SCHEMBL31562044 | 0.71 | KDM4E (0.56) | KDM4EPOLBMAPTTDP1SMN1; SMN2 | |
| SCHEMBL14383487 | 0.68 | GSTO1 (0.48) | KDM4EPOLBMAPTTDP1PTPN1 | |
| SCHEMBL3360546 | 0.68 | PTPN1 (0.43) | POLBMAPTTDP1SMN1; SMN2PTPN1 | |
| SCHEMBL10628786 | 0.67 | KDM4E (0.39) | KDM4EPOLBMAPTTDP1SMN1; SMN2 | |
| SCHEMBL8589614 | 0.66 | SMN1; SMN2 (0.49) | KDM4EPOLBMAPTTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006548-A | Hyaluronidase inhibitors, antiallergens, immunomodulators | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0153850-B1 | ACRYLAMIDOBENZOIC ACID DERIVATIVES AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |