Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | KDM6B | O15054 | 1/20 | 0.68 |
| ▸ | KDM4A | O75164 | 1/20 | 0.68 |
| ▸ | KDM5C | P41229 | 1/20 | 0.68 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.68 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742362 | 0.88 | AURKA (0.56) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL3794871 | 0.87 | KDM4E (0.60) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL28603982 | 0.82 | KDM4E (0.62) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL5053292 | 0.82 | KDM4E (0.59) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL5053005 | 0.82 | KDM4E (0.62) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL22836964 | 0.81 | KDM4E (0.61) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL22836969 | 0.81 | ALDH1A1 (0.62) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL22852474 | 0.81 | KDM4E (0.61) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL18247811 | 0.81 | KDM4C (1.00) | KDM4EKDM6BKDM4AKDM5CKDM4D | |
| SCHEMBL29576784 | 0.81 | KDM4C (1.00) | KDM4EKDM6BKDM4AKDM5CKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150328329-A1 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | American University of Cairo (EG) | 2015-11-19 | — | — | US | disclosed |
| WO-2014081856-A2 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | AZZAZY HASSAN (EG) | 2014-05-30 | — | — | WO | disclosed |
| WO-2012033878-A2 | COMPOUNDS AND METHODS FOR ACEMIF INHIBITION AND THE TREATMENT OF PARASITES | YALE UNIVERSITY (US) | 2012-03-15 | — | — | WO | disclosed |
| CN-1234792-A | Nitrate ester derivatives and their use in the treatment of urinary incontinence and other disorders | NICOX SA (FR) | 1999-11-10 | — | — | CN | disclosed |
| EP-0036145-B1 | AN ORALLY ADMINISTERED DRUG FORM COMPRISING A POLAR BIOACTIVE AGENT AND AN ADJUVANT | INTERx RESEARCH CORPORATION (US) | 1985-05-29 | — | — | EP | disclosed |
| EP-0031561-B1 | A RECTALLY ADMINISTERED SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT | MERCK & CO. INC. (US) | 1985-04-10 | — | — | EP | disclosed |