Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.38 |
| ▸ | ITGAL | P20701 | 4/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944103 | 1.00 | MAPT (0.39) | MAPTPOLBKDM4EAPAF1RECQL | |
| SCHEMBL3945354 | 0.92 | MEN1 (0.40) | MAPTPOLBKDM4EAPAF1RECQL | |
| SCHEMBL3943362 | 0.92 | MEN1 (0.41) | MAPTPOLBKDM4EAPAF1RECQL | |
| SCHEMBL3936356 | 0.90 | KMT2A (0.41) | MAPTKDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL13912874 | 0.90 | ECE1 (0.40) | MAPTKDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL3943652 | 0.90 | CTSL (0.41) | MAPTPOLBKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL3941151 | 0.90 | MEN1 (0.42) | MAPTPOLBKDM4EAPAF1RECQL | |
| SCHEMBL3939353 | 0.90 | MEN1 (0.42) | MAPTPOLBKDM4EL3MBTL1HPGD | |
| SCHEMBL3943481 | 0.88 | MEN1 (0.43) | MAPTPOLBKDM4EAPAF1RECQL | |
| SCHEMBL3945226 | 0.88 | MMP9 (0.40) | MAPTPOLBKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |