Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541407 | 0.95 | FFAR1 (0.36) | FFAR1TSHRL3MBTL1 | |
| SCHEMBL6883859 | 0.74 | FFAR1 (0.56) | FFAR1 | |
| SCHEMBL4535960 | 0.71 | LTA4H (0.34) | TSHRL3MBTL1 | |
| SCHEMBL5372941 | 0.71 | L3MBTL1 (0.35) | TSHRL3MBTL1 | |
| SCHEMBL15807936 | 0.69 | CYP1A2 (0.47) | L3MBTL1 | |
| SCHEMBL22388832 | 0.69 | CYP1A2 (0.47) | L3MBTL1 | |
| SCHEMBL4537514 | 0.69 | LTA4H (0.38) | TSHR | |
| SCHEMBL1778386 | 0.68 | L3MBTL1 (0.40) | L3MBTL1 | |
| SCHEMBL1778381 | 0.68 | L3MBTL1 (0.40) | L3MBTL1 | |
| SCHEMBL3640235 | 0.68 | FFAR1 (0.44) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |