Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4539563 | 0.88 | EPHX2 (0.56) | EPHX2EPHX1 | |
| SCHEMBL4532833 | 0.87 | KMT2A (0.53) | EPHX2EPHX1 | |
| SCHEMBL4537539 | 0.86 | EPHX2 (0.56) | EPHX2EPHX1 | |
| SCHEMBL4537182 | 0.86 | EPHX2 (0.58) | EPHX2EPHX1 | |
| SCHEMBL4537075 | 0.84 | CYP19A1 (0.53) | EPHX2EPHX1 | |
| SCHEMBL8062507 | 0.83 | EPHX2 (0.53) | EPHX2EPHX1 | |
| SCHEMBL4535739 | 0.83 | EPHX2 (0.54) | EPHX2EPHX1 | |
| SCHEMBL4539990 | 0.82 | USP2 (0.56) | EPHX2EPHX1 | |
| SCHEMBL8059951 | 0.82 | EPHX2 (0.60) | EPHX2EPHX1 | |
| SCHEMBL4533513 | 0.82 | EPHX2 (0.60) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | claimed |
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |