Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43296 | 0.86 | ALDH1A1 (0.39) | ALDH1A1NCF1GAASMN1; SMN2ALOX15 | |
| SCHEMBL2254744 | 0.84 | — | — | |
| SCHEMBL8272496 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NCF1 | |
| SCHEMBL8439285 | 0.79 | NCF1 (0.41) | ALDH1A1NCF1GAASMN1; SMN2ALOX15 | |
| SCHEMBL26042902 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NCF1GAASMN1; SMN2ALOX15 | |
| SCHEMBL23588990 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NCF1SMN1; SMN2 | |
| SCHEMBL358559 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NCF1 | |
| SCHEMBL18379027 | 0.79 | NCF1 (0.41) | ALDH1A1NCF1GAASMN1; SMN2ALOX15 | |
| SCHEMBL1908657 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NCF1 | |
| SCHEMBL25853905 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NCF1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071691-A2 | OXINDOLE DERIVATIVES AND THE USE THEREOF AS A MEDICATION | ABBOTT GMBH & CO. KG (DE) | 2009-06-11 | — | — | WO | disclosed |