Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537251 | 1.00 | MKNK1 (0.40) | MKNK1MCHR1KCNH2AURKBCYSLTR2 | |
| SCHEMBL4534768 | 0.85 | MCHR1 (0.44) | MCHR1KCNH2 | |
| SCHEMBL4534764 | 0.85 | MCHR1 (0.44) | MCHR1KCNH2 | |
| SCHEMBL13677512 | 0.84 | MCHR1 (0.46) | MCHR1KCNH2 | |
| SCHEMBL4540709 | 0.75 | MCHR1 (0.46) | MCHR1KCNH2 | |
| SCHEMBL4540712 | 0.75 | MCHR1 (0.46) | MCHR1KCNH2 | |
| SCHEMBL2887697 | 0.69 | MCHR1 (0.59) | MCHR1KCNH2 | |
| SCHEMBL2887698 | 0.69 | MCHR1 (0.59) | MCHR1KCNH2 | |
| SCHEMBL4535271 | 0.67 | MCHR1 (0.57) | MCHR1KCNH2 | |
| SCHEMBL4526443 | 0.66 | MCHR1 (0.56) | MCHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | MSD K.K. (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1939194-A1 | BICYCLIC AROMATIC SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | PYCR1, CHRM1, MTR | MKNK1 1635/4885MCHR1 357/4885KCNH2 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.