Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535721 | 0.94 | EPHX2 (0.63) | EPHX2EPHX1 | |
| SCHEMBL8048274 | 0.83 | EPHX1 (0.69) | EPHX2EPHX1 | |
| SCHEMBL5144210 | 0.81 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL4537057 | 0.80 | EPHX1 (0.57) | EPHX2EPHX1 | |
| SCHEMBL8233455 | 0.79 | EPHX1 (1.00) | EPHX2EPHX1 | |
| SCHEMBL8060837 | 0.79 | EPHX2 (0.70) | EPHX2EPHX1 | |
| SCHEMBL8925131 | 0.78 | EPHX1 (1.00) | EPHX2EPHX1 | |
| SCHEMBL4541309 | 0.78 | EPHX1 (0.70) | EPHX2EPHX1 | |
| SCHEMBL4188068 | 0.77 | EPHX1 (1.00) | EPHX2EPHX1 | |
| SCHEMBL5146574 | 0.76 | EPHX1 (1.00) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | claimed |
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |