Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 19/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 18/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541309 | 0.84 | EPHX1 (0.70) | EPHX1EPHX2 | |
| SCHEMBL4537349 | 0.83 | EPHX2 (0.69) | EPHX1EPHX2 | |
| SCHEMBL4538172 | 0.82 | EPHX1 (0.58) | EPHX1EPHX2LMNA | |
| SCHEMBL8925131 | 0.82 | EPHX1 (1.00) | EPHX1EPHX2 | |
| SCHEMBL652237 | 0.82 | EPHX1 (1.00) | EPHX1EPHX2 | |
| SCHEMBL8064838 | 0.81 | EPHX1 (0.68) | EPHX1EPHX2 | |
| SCHEMBL3213643 | 0.80 | EPHX2 (1.00) | EPHX1EPHX2LMNA | |
| SCHEMBL4533513 | 0.80 | EPHX2 (0.60) | EPHX1EPHX2 | |
| SCHEMBL8059951 | 0.80 | EPHX2 (0.60) | EPHX1EPHX2 | |
| SCHEMBL4540420 | 0.80 | EPHX1 (0.63) | EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |