SCHEMBL4537376

SCHEMBL4537376

Cc1c[nH]cc1C(=O)Oc1ccc(N=Nc2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.45
RAB9A P51151 4/20 0.45
TDP1 Q9NUW8 2/20 0.45
CASP3 P42574 2/20 0.45
SENP8 Q96LD8 2/20 0.45
SENP7 Q9BQF6 2/20 0.45
SENP6 Q9GZR1 2/20 0.45
KDM4E B2RXH2 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ELANE P08246 1/20 0.43
NOTUM Q6P988 1/20 0.42
NR4A2 P43354 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4537374 1.00 MAPT (0.45) MAPTRAB9ATDP1CASP3SENP8
SCHEMBL4527922 0.86 MAPT (0.54) MAPTTDP1KDM4ENOTUMNR4A2
SCHEMBL28075523 0.76 HPGD (0.72) MAPTRAB9ATDP1CASP3SENP8
SCHEMBL27279499 0.75 MAPT (0.66) MAPTRAB9ATDP1CASP3SENP8
SCHEMBL14130027 0.75 MAPT (0.66) MAPTRAB9ATDP1CASP3SENP8
SCHEMBL27677192 0.75 MAPT (0.61) MAPTRAB9ATDP1CASP3SENP8
SCHEMBL14130171 0.73 NSD2 (0.59) MAPTRAB9ATDP1CASP3SENP8
SCHEMBL29154399 0.73 ELANE (0.61) MAPTRAB9ATDP1CASP3SENP8
SCHEMBL12479221 0.73 ELANE (0.61) MAPTRAB9ATDP1CASP3SENP8
SCHEMBL1096614 0.72 TRPA1 (0.55) MAPTRAB9ATDP1CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090014920-A1 POLYMER FILAMENTS MASSEY UNIVERSITY (NZ) 2009-01-15 US claimed
WO-2006001719-A1 POLYMER FILAMENTS MASSEY UNIVERSITY (NZ) 2006-01-05 WO claimed
US-20090014920-A1 POLYMER FILAMENTS MASSEY UNIVERSITY (NZ) 2009-01-15 US disclosed
WO-2006001719-A1 POLYMER FILAMENTS MASSEY UNIVERSITY (NZ) 2006-01-05 WO disclosed
EP-0332704-B1 PROCESS FOR PRODUCING CONDUCTIVE POLYMER FILM NIPPON SODA CO (JP) 1994-12-21 EP disclosed
US-5306443-A Dissolving monomer with metal containing oxidizing agent in sufficient solvent to prevent polymerization; removal of solvent NIPPON SODA CO., LTD. (JP) 1994-04-26 US disclosed
EP-0332704-A1 PROCESS FOR PRODUCING CONDUCTIVE POLYMER FILM NIPPON SODA CO., LTD. (JP) 1989-09-20 EP disclosed