SCHEMBL27279499

SCHEMBL27279499

O=C(Oc1ccc(/N=N/c2ccccc2)cc1)c1ccc(/N=N/c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.66
RAB9A P51151 2/20 0.66
L3MBTL1 Q9Y468 2/20 0.66
CASP3 P42574 1/20 0.66
SENP8 Q96LD8 1/20 0.66
SENP7 Q9BQF6 1/20 0.66
SENP6 Q9GZR1 1/20 0.66
PRSS1 P07477 7/20 0.63
ACR P10323 5/20 0.63
TMPRSS15 P98073 2/20 0.63
PARP10 Q53GL7 1/20 0.61
TRPA1 O75762 1/20 0.60
F2 P00734 3/20 0.59
PRSS2 P07478 3/20 0.59
PRSS3 P35030 3/20 0.59
KMT2A Q03164 4/20 0.54
MEN1 O00255 2/20 0.54
HGFAC Q04756 2/20 0.54
TDP1 Q9NUW8 2/20 0.53
ALDH1A1 P00352 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14130027 1.00 MAPT (0.66) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL27677192 0.96 MAPT (0.61) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL14130228 0.95 MAPT (0.60) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL14130095 0.91 PRSS1 (0.58) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL14130427 0.91 MAPT (0.64) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL14130171 0.91 NSD2 (0.59) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL14130182 0.88 MAPT (0.52) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL14130099 0.88 MAPT (0.61) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL14130230 0.88 MAPT (0.61) MAPTRAB9AL3MBTL1CASP3SENP8
SCHEMBL1923594 0.85 PRSS1 (0.68) MAPTRAB9AL3MBTL1CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1625688-A Folate assay AXIS SHIELD ASA (NO) 2005-06-08 CN claimed
CN-101243080-A Pyrazolo[3,4-B]pyridin-2-yl]-benzoic acid derivatives as HIV integrase inhibitors AMBRILIA BIOPHARMA INC (CA) 2008-08-13 CN disclosed
CN-1625688-A Folate assay AXIS SHIELD ASA (NO) 2005-06-08 CN disclosed
CN-1020472-C MAMMALIAN INTERLEUKIN-4 SCHERING BIOTECH CORP (US) 1993-05-05 CN disclosed
CN-86108593-A SNAKE VENOM GROWTH ARRESTING PEPTIDE 1987-09-30 CN disclosed