Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5117966 | 0.87 | THRA (0.59) | ALDH1A1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL11887834 | 0.70 | MAPT (0.77) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6038476 | 0.69 | CCR4 (0.50) | ALDH1A1MAPTLMNASMN1; SMN2NR3C2 | |
| Acetic Acid SCHEMBL27492277 | 0.68 | ALDH1A1 (0.73) | ALDH1A1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL6831724 | 0.68 | ALDH1A1 (0.68) | ALDH1A1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL5866256 | 0.68 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL5866258 | 0.68 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL5866263 | 0.68 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL328329 | 0.67 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5866324 | 0.67 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080835-A1 | THYROMIMETRIC COMPOUNDS IN TREATMENT OF DISEASE RELATED TO SONIC HEDGEHOG SIGNALLING | KARO BIO AB (SE) | 2009-07-02 | — | — | WO | disclosed |