Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.81 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | CCR9 | P51686 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191922 | 0.88 | CCR2 (0.76) | CCR2GPR35ABCB11CCR9 | |
| SCHEMBL27658570 | 0.87 | CCR2 (0.82) | CCR2GPR35ABCB11CCR9 | |
| SCHEMBL6306929 | 0.86 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL4537700 | 0.86 | CCR2 (0.76) | CCR2ABCB11 | |
| SCHEMBL6303108 | 0.86 | CCR2 (0.79) | CCR2GPR35ABCB11 | |
| SCHEMBL3209668 | 0.85 | CCR2 (0.74) | CCR2ABCB11 | |
| SCHEMBL3198968 | 0.85 | CCR2 (0.70) | CCR2GPR35ABCB11 | |
| SCHEMBL8692473 | 0.84 | CCR2 (0.72) | CCR2ABCB11CCR9 | |
| SCHEMBL29845455 | 0.83 | CCR2 (0.81) | CCR2GPR35CCR9 | |
| SCHEMBL4201841 | 0.83 | CCR2 (0.77) | CCR2ABCB11CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | claimed |
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | disclosed |