Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209668 | 0.91 | CCR2 (0.74) | CCR2ABCB11 | |
| SCHEMBL27658570 | 0.87 | CCR2 (0.82) | CCR2ABCB11 | |
| SCHEMBL6308068 | 0.87 | CCR2 (0.73) | CCR2PTGS2PTGS1ABCB11 | |
| SCHEMBL6306929 | 0.86 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL2005378 | 0.86 | CCR2 (0.73) | CCR2ABCB11 | |
| SCHEMBL4537478 | 0.86 | CCR2 (0.81) | CCR2ABCB11 | |
| SCHEMBL4201841 | 0.86 | CCR2 (0.77) | CCR2ABCB11 | |
| SCHEMBL7076755 | 0.86 | CCR2 (1.00) | CCR2ABCB11 | |
| SCHEMBL8692473 | 0.84 | CCR2 (0.72) | CCR2ABCB11 | |
| SCHEMBL7008246 | 0.83 | CCR2 (0.81) | CCR2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | claimed |
| WO-2009063495-A2 | SUBSTITUTED INDOLE AND ITS DERIVATIVES AS CANNABINOID MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2009-05-22 | — | — | WO | disclosed |