Diphenylmethane

Diphenylmethane

SCHEMBL4537622

O=C=Nc1ccc(Cc2ccc(N=C=O)cc2)cc1.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.83
TSHR P16473 1/20 0.83
CYP1A2 P05177 1/20 0.59
SLC22A2 O15244 1/20 0.50
CALM1 P0DP23 1/20 0.50
CYP2C9 P11712 1/20 0.46
PLA2G10 O15496 1/20 0.42
PLA2G2A P14555 1/20 0.42
LMNA P02545 1/20 0.42
LTA4H P09960 1/20 0.41
IDH1 O75874 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
PPARG P37231 3/20 0.39
PPARA Q07869 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL510929 1.00 CYP3A4 (0.83) CYP3A4TSHRCYP1A2SLC22A2CALM1
Diphenylmethane SCHEMBL28882075 0.92 CYP3A4 (0.70) CYP3A4TSHRCYP1A2SLC22A2CALM1
SCHEMBL19943 0.91 CYP3A4 (1.00) CYP3A4TSHRCYP1A2SLC22A2CALM1
SCHEMBL12852256 0.91 CYP3A4 (1.00) CYP3A4TSHRCYP1A2SLC22A2CALM1
SCHEMBL2044965 0.91 CYP3A4 (1.00) CYP3A4TSHRCYP1A2SLC22A2CALM1
SCHEMBL1396496 0.91 CYP3A4 (1.00) CYP3A4TSHRCYP1A2SLC22A2CALM1
SCHEMBL30634516 0.89 CYP3A4 (0.95) CYP3A4TSHRCYP1A2SLC22A2CALM1
Water SCHEMBL8522858 0.89 CYP3A4 (0.95) CYP3A4TSHRCYP1A2SLC22A2CALM1
Ammonia Solution, Strong SCHEMBL3504367 0.89 CYP3A4 (0.95) CYP3A4TSHRCYP1A2SLC22A2CALM1
SCHEMBL13869615 0.88 CYP3A4 (0.77) CYP3A4TSHRCYP1A2SLC22A2CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3606996-A1 INSULATING GLASS SEALANTS BASED ON POLYURETHANES AND ORGANICALLY-MODIFIED NANOCLAYS Fina Technology, Inc. (US) 2020-02-12 EP disclosed
US-10370523-B2 Insulating glass sealants based on polyurethanes and organically-modified nanoclays FINA TECHNOLOGY, INC. (US) 2019-08-06 US disclosed
WO-2018187086-A1 INSULATING GLASS SEALANTS BASED ON POLYURETHANES AND ORGANICALLY-MODIFIED NANOCLAYS FINA TECHNOLOGY, INC. (US) 2018-10-11 WO disclosed
US-20180282524-A1 INSULATING GLASS SEALANTS BASED ON POLYURETHANES AND ORGANICALLY-MODIFIED NANOCLAYS FINA TECHNOLOGY, INC. (US) 2018-10-04 US disclosed
CN-107709396-A urethane (meth) acrylate resin and laminated film DIC株式会社 2018-02-16 CN disclosed
EP-2900724-B1 POLYURETHANE BASED INSULATED GLASS SEALANT DOW GLOBAL TECHNOLOGIES LLC (US) 2018-01-10 EP disclosed
US-9546307-B2 Polyurethane based insulated glass sealant DOW GLOBAL TECHNOLOGIES LLC 2017-01-17 US disclosed
US-9284458-B2 Silicone backbone prepolymers for flame resistant polyurethanes DOW GLOBAL TECHNOLOGIES LLC (US) 2016-03-15 US disclosed
US-20150218428-A1 POLYURETHANE BASED INSULATED GLASS SEALANT DOW GLOBAL TECHNOLOGIES LLC 2015-08-06 US disclosed
EP-2900724-A1 POLYURETHANE BASED INSULATED GLASS SEALANT Dow Global Technologies LLC (US) 2015-08-05 EP disclosed
EP-2638090-B1 POLYURETHANE BASED INSULATED GLASS SEALANT DOW GLOBAL TECHNOLOGIES LLC (US) 2015-02-11 EP disclosed
EP-2726527-A1 SILICONE BACKBONE PREPOLYMERS FOR FLAME RESISTANT POLYURETHANES Dow Global Technologies LLC (US) 2014-05-07 EP disclosed
US-20140113991-A1 SILICONE BACKBONE PREPOLYMERS FOR FLAME RESISTANT POLYURETHANES DOW GLOBAL TECHNOLOGIES LLC (US) 2014-04-24 US disclosed
EP-2638090-A1 POLYURETHANE BASED INSULATED GLASS SEALANT Dow Global Technologies LLC (US) 2013-09-18 EP disclosed
US-20130216840-A1 POLYURETHANE BASED INSULATED GLASS SEALANT DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-22 US disclosed
EP-2627688-A1 POLYURETHANE ELASTOMER COATINGS Dow Global Technologies LLC (US) 2013-08-21 EP disclosed
US-20130197159-A1 POLYURETHANE ELASTOMER COATINGS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-01 US disclosed
WO-2013003054-A1 SILICONE BACKBONE PREPOLYMERS FOR FLAME RESISTANT POLYURETHANES DOW GLOBAL TECHNOLOGIES LLC (US) 2013-01-03 WO disclosed
WO-2012064971-A1 POLYURETHANE BASED INSULATED GLASS SEALANT DOW GLOBAL TECHNOLOGIES LLC (US) 2012-05-18 WO disclosed
WO-2012051135-A1 POLYURETHANE ELASTOMER COATINGS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-19 WO disclosed