Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722644 | 0.85 | TRPV3 (0.40) | PDCD1LG2CD274TRPV3 | |
| SCHEMBL3710213 | 0.78 | PDCD1LG2 (0.37) | PDCD1LG2CD274 | |
| SCHEMBL22885900 | 0.70 | PDCD1LG2 (0.37) | PDCD1LG2CD274 | |
| SCHEMBL3717472 | 0.66 | PDCD1LG2 (0.36) | PDCD1LG2CD274 | |
| SCHEMBL3741159 | 0.64 | PDCD1LG2 (0.38) | PDCD1LG2CD274 | |
| SCHEMBL3720284 | 0.63 | PDCD1LG2 (0.34) | PDCD1LG2CD274TRPV3 | |
| SCHEMBL3719113 | 0.62 | CD274 (0.38) | PDCD1LG2CD274 | |
| SCHEMBL3724644 | 0.62 | ADORA2B (0.36) | PDCD1LG2CD274TRPV3 | |
| SCHEMBL844505 | 0.62 | KMT2A (0.31) | — | |
| SCHEMBL30968506 | 0.62 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012064269-A1 | COMPOUNDS AND THEIR USE FOR TREATMENT OF Αβ-RELATED DISEASES | ASTRAZENECA AB (SE) | 2012-05-18 | — | — | WO | disclosed |