Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45399 | 0.92 | MAPT (0.41) | DNM1MAPTTSHRFDPSLMNA | |
| SCHEMBL7688271 | 0.90 | MAPT (0.45) | DNM1MAPTTSHRFDPSLMNA | |
| SCHEMBL1697637 | 0.90 | MAPT (0.45) | DNM1MAPTTSHRFDPSLMNA | |
| SCHEMBL27855630 | 0.90 | MAPT (0.45) | DNM1MAPTTSHRFDPSLMNA | |
| SCHEMBL27453782 | 0.90 | MAPT (0.45) | DNM1MAPTTSHRFDPSLMNA | |
| SCHEMBL27974305 | 0.90 | MAPT (0.45) | DNM1MAPTTSHRFDPSLMNA | |
| SCHEMBL30892684 | 0.90 | MAPT (0.45) | DNM1MAPTTSHRFDPSLMNA | |
| SCHEMBL9946309 | 0.82 | — | — | |
| SCHEMBL1470817 | 0.82 | — | — | |
| SCHEMBL23825068 | 0.79 | FDPS (0.36) | DNM1ALDH1A1MAPTCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4692032-A2 | SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF | Honeywell International Inc. (US) | 2026-02-11 | — | — | EP | claimed |
| EP-3737660-B1 | SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF | HONEYWELL INT INC (US) | 2025-11-05 | — | — | EP | claimed |
| CN-117986081-A | System and method for reducing impurity formation during dehydrochlorination of 244bb to 1234yf | 霍尼韦尔国际公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117986080-A | System and method for reducing impurity formation during dehydrochlorination of 244bb to 1234yf | 霍尼韦尔国际公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117986082-A | Compositions comprising 2-chloro-1, 2-tetrafluoropropane (HCFC-244 bb) | 霍尼韦尔国际公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117986083-A | Compositions comprising 2-chloro-1, 2-tetrafluoropropane (HCFC-244 bb) | 霍尼韦尔国际公司 | 2024-05-07 | — | — | CN | claimed |
| EP-3737659-A1 | COMPOSITIONS CONTAINING 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE (HCFC-244BB) | Honeywell International Inc. (US) | 2020-11-18 | — | — | EP | claimed |
| EP-3737660-A1 | SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF | Honeywell International Inc. (US) | 2020-11-18 | — | — | EP | claimed |
| CN-111699168-A | Systems and methods for reducing impurity formation during dehydrochlorination of 244bb to 1234yf | 霍尼韦尔国际公司 | 2020-09-22 | — | — | CN | claimed |
| CN-111699167-A | Compositions comprising 2-chloro-1, 1,1, 2-tetrafluoropropane (HCFC-244bb) | 霍尼韦尔国际公司 | 2020-09-22 | — | — | CN | claimed |
| WO-2019136408-A1 | COMPOSITIONS CONTAINING 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) | HONEYWELL INTERNATIONAL INC. (US) | 2019-07-11 | — | — | WO | claimed |
| WO-2019136410-A1 | SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244bb DEHYDROCHLORINATION TO 1234yf | HONEYWELL INTERNATIONAL INC. (US) | 2019-07-11 | — | — | WO | claimed |
| US-20190210945-A1 | COMPOSITIONS CONTAINING 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) | SOLSTICE ADVANCED MATERIALS US, INC. | 2019-07-11 | — | — | US | claimed |
| US-10246389-B1 | Compositions containing 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) | HONEYWELL INTERNATIONAL INC. (US) | 2019-04-02 | — | — | US | claimed |
| US-20070196457-A1 | Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs | NUVO RESEARCH INC. (CA) | 2007-08-23 | — | — | US | claimed |
| US-6277937-B1 | CHARGING REACTOR WITH AQUEOUS MEDIUM COMPRISING SUSPENSION STABILIZER; CHARGING GASEOUS MONOMER MIXTURE COMPRISING VINYLIDENE FLUORIDE MAJOR AND FLUORINATED MAJOR, MIXING; INITIATING POLYMERIZATION; ADDING CURE SITE MONOMER | DUPONT DOW ELASTOMERS, L.L.C. | 2001-08-21 | — | — | US | claimed |
| EP-4692032-A2 | SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF | Honeywell International Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-3737660-B1 | SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF | HONEYWELL INT INC (US) | 2025-11-05 | — | — | EP | disclosed |
| US-4693799-A | LOW TEMPERATURE PULSE DISCHARGING | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-09-15 | — | — | US | disclosed |
| US-4582592-A | EXTENDING EFFECTIVE LIFE OF ALUMINA-SUPPORTED CATALYST | CHEVRON RESEARCH COMPANY (US) | 1986-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190210945-A1 | COMPOSITIONS CONTAINING 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) | HCFC1, FGB, CYP2F1 | DNM1 2749/4885ALDH1A1 1776/4885MAPT 4431/4885 |
| US-10246389-B1 | Compositions containing 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) | HCFC1, FGB, CYP2F1 | DNM1 2749/4885ALDH1A1 1776/4885MAPT 4431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.