SCHEMBL45381

SCHEMBL45381

FCCCCC(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1697639 0.97
SCHEMBL45400 0.97
SCHEMBL28783839 0.97
SCHEMBL4442351 0.90
SCHEMBL12468957 0.82
SCHEMBL25235511 0.80
SCHEMBL22042309 0.80
SCHEMBL45437 0.80
SCHEMBL45269 0.80
SCHEMBL45378 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692032-A2 SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF Honeywell International Inc. (US) 2026-02-11 EP claimed
EP-3737660-B1 SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF HONEYWELL INT INC (US) 2025-11-05 EP claimed
CN-117986083-A Compositions comprising 2-chloro-1, 2-tetrafluoropropane (HCFC-244 bb) 霍尼韦尔国际公司 2024-05-07 CN claimed
CN-117986081-A System and method for reducing impurity formation during dehydrochlorination of 244bb to 1234yf 霍尼韦尔国际公司 2024-05-07 CN claimed
CN-117986080-A System and method for reducing impurity formation during dehydrochlorination of 244bb to 1234yf 霍尼韦尔国际公司 2024-05-07 CN claimed
CN-117986082-A Compositions comprising 2-chloro-1, 2-tetrafluoropropane (HCFC-244 bb) 霍尼韦尔国际公司 2024-05-07 CN claimed
EP-3737659-A1 COMPOSITIONS CONTAINING 2-CHLORO-1,1,1,2-TETRAFLUOROPROPANE (HCFC-244BB) Honeywell International Inc. (US) 2020-11-18 EP claimed
EP-3737660-A1 SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF Honeywell International Inc. (US) 2020-11-18 EP claimed
CN-111699167-A Compositions comprising 2-chloro-1, 1,1, 2-tetrafluoropropane (HCFC-244bb) 霍尼韦尔国际公司 2020-09-22 CN claimed
CN-111699168-A Systems and methods for reducing impurity formation during dehydrochlorination of 244bb to 1234yf 霍尼韦尔国际公司 2020-09-22 CN claimed
WO-2019136408-A1 COMPOSITIONS CONTAINING 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) HONEYWELL INTERNATIONAL INC. (US) 2019-07-11 WO claimed
WO-2019136410-A1 SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244bb DEHYDROCHLORINATION TO 1234yf HONEYWELL INTERNATIONAL INC. (US) 2019-07-11 WO claimed
US-20190210945-A1 COMPOSITIONS CONTAINING 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) SOLSTICE ADVANCED MATERIALS US, INC. 2019-07-11 US claimed
US-10246389-B1 Compositions containing 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) HONEYWELL INTERNATIONAL INC. (US) 2019-04-02 US claimed
US-6277937-B1 CHARGING REACTOR WITH AQUEOUS MEDIUM COMPRISING SUSPENSION STABILIZER; CHARGING GASEOUS MONOMER MIXTURE COMPRISING VINYLIDENE FLUORIDE MAJOR AND FLUORINATED MAJOR, MIXING; INITIATING POLYMERIZATION; ADDING CURE SITE MONOMER DUPONT DOW ELASTOMERS, L.L.C. 2001-08-21 US claimed
EP-4692032-A2 SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF Honeywell International Inc. (US) 2026-02-11 EP disclosed
EP-3737660-B1 SYSTEMS AND METHODS FOR REDUCING THE FORMATION OF IMPURITIES DURING 244BB DEHYDROCHLORINATION TO 1234YF HONEYWELL INT INC (US) 2025-11-05 EP disclosed
US-4910041-A Generated arced plasma; applying a magnetic field JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-03-20 US disclosed
US-4693799-A LOW TEMPERATURE PULSE DISCHARGING JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-09-15 US disclosed
US-4582592-A EXTENDING EFFECTIVE LIFE OF ALUMINA-SUPPORTED CATALYST CHEVRON RESEARCH COMPANY (US) 1986-04-15 US disclosed