SCHEMBL45382

SCHEMBL45382

NC(Cc1cc2ccccc2[nH]1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.54
PKM P14618 1/20 0.54
PTGS1 P23219 1/20 0.54
XIAP P98170 1/20 0.54
SLC7A5 Q01650 1/20 0.54
ADAMTS4 O75173 1/20 0.54
LOXL2 Q9Y4K0 1/20 0.53
DPP4 P27487 2/20 0.51
KDM4E B2RXH2 3/20 0.49
MAPT P10636 2/20 0.49
TSHR P16473 2/20 0.49
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
MPO P05164 1/20 0.49
BLM P54132 1/20 0.49
PMP22 Q01453 1/20 0.49
KMT2A Q03164 1/20 0.49
HIF1A Q16665 1/20 0.49
MTNR1A P48039 1/20 0.48
MTNR1B P49286 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4393088 1.00 ALPI (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL29574121 1.00 ALPI (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL2700469 1.00 ALPI (0.54) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL29440959 1.00 ALPI (0.54) ALPIPKMPTGS1XIAPSLC7A5
Tryptophan SCHEMBL679476 0.86 KMT2A (0.74) PKMKDM4EMAPTTSHRMEN1
SCHEMBL12936626 0.86 MTNR1A (0.54) ADAMTS4LOXL2DPP4KDM4EMAPT
SCHEMBL5322847 0.85 MTNR1A (0.52) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL1332798 0.83 ADAMTS4 (0.55) ADAMTS4LOXL2KDM4EMAPTTSHR
SCHEMBL29396939 0.83 ADAMTS4 (0.55) ADAMTS4LOXL2KDM4EMAPTTSHR
SCHEMBL5172404 0.83 ADAMTS4 (0.55) ADAMTS4LOXL2KDM4EMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823093-A Heterocyclic dibasic acid containing nonpolar hydrophobic group and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2025-04-15 CN claimed
CN-117186343-B Transparent polyamide and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-03-12 CN claimed
CN-117186343-A Transparent polyamide and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-12-08 CN claimed
CN-114875087-A Method for synthesizing 5-hydroxy beta-indolyl alanine by using beta-indolyl alanine as substrate and application thereof 河北维达康生物科技有限公司 2022-08-09 CN claimed
CN-113651946-A Epoxy resin curing agent and preparation method and application thereof 万华化学集团股份有限公司 2021-11-16 CN claimed
EP-0454651-B1 Novel platelet-aggregation inhibitors MONSANTO CO (US) 1999-07-28 EP claimed
EP-0804463-A1 NEUROKININE (TACHYKININE) ANTAGONISTS BOEHRINGER INGELHEIM KG (DE) 1997-11-05 EP claimed
WO-1995030687-A1 NEUROKININE (TACHYKININE) ANTAGONISTS BOEHRINGER INGELHEIM KG (DE) 1995-11-16 WO claimed
EP-0454651-A2 Novel platelet-aggregation inhibitors MONSANTO COMPANY (US) 1991-10-30 EP claimed
US-5037808-A Indolyl platelet-aggregation inhibitors MONSANTO CO. (US) 1991-08-06 US claimed
CN-118755083-B Bio-based polyamide polyester, and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2026-05-12 CN disclosed
EP-3604503-B1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO KK (JP) 2026-03-18 EP disclosed
US-20250270512-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO CO., INC. (JP) 2025-08-28 US disclosed
CN-119823093-A Heterocyclic dibasic acid containing nonpolar hydrophobic group and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2025-04-15 CN disclosed
CN-118755083-A Bio-based polyamide polyester, and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-10-11 CN disclosed
US-5091396-A Guanidinoalkanoylaspartylpyridine derivatives; anticoagulants MONSANTO CO. (US) 1992-02-25 US disclosed
EP-0454651-A2 Novel platelet-aggregation inhibitors MONSANTO COMPANY (US) 1991-10-30 EP disclosed
US-5037808-A Indolyl platelet-aggregation inhibitors MONSANTO CO. (US) 1991-08-06 US disclosed
US-4190585-A 2,3-DIHYDRO-2,5-FURAN DICARBOXYLIC ACID, PHENYL HYDRAZINE, SULFURIC ACID LONZA LTD. (CH) 1980-02-26 US disclosed
US-4044125-A GLUTAMIC ACID, GLYCINE, ASPARTIC ACID, OR ALANINE HYDROCHLORIDE, LYSINE DIHYDROCHLORIDE ELI LILLY AND COMPANY (US) 1977-08-23 US disclosed