Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355595 | 0.90 | POLB (0.54) | PTPN2PTPN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4520212 | 0.89 | PTPN2 (0.47) | PTPN2PTPN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL13586060 | 0.89 | SMN1; SMN2 (0.47) | PTPN2PTPN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4538611 | 0.87 | HPGD (0.42) | PTPN2PTPN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL13586029 | 0.87 | PTPN2 (0.44) | PTPN2PTPN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL13586043 | 0.86 | NPY2R (0.43) | PTPN2PTPN1ALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL13586061 | 0.86 | MEN1 (0.49) | PTPN2PTPN1ALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL4533655 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP2C19HTTMEN1KMT2A | |
| SCHEMBL4537918 | 0.85 | PTPN2 (0.43) | PTPN2PTPN1ALDH1A1SMN1; SMN2ACHE | |
| SCHEMBL4534565 | 0.85 | KDM4E (0.40) | HPGDALDH1A1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |