Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4360439 | 0.91 | TSHR (0.44) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL4522943 | 0.90 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL4531625 | 0.90 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL4533655 | 0.90 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2HTTKMT2AGPR119 | |
| SCHEMBL4349657 | 0.89 | GPR119 (0.44) | KDM4EALDH1A1SMN1; SMN2GPR119GAA | |
| SCHEMBL4356877 | 0.88 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL4354226 | 0.88 | KDM4E (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL4356808 | 0.87 | SETD7 (0.45) | KDM4EALDH1A1HPGDLMNAHTT | |
| SCHEMBL4358687 | 0.87 | SMN1; SMN2 (0.46) | KDM4EALDH1A1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL4524446 | 0.86 | GPR119 (0.40) | KDM4EALDH1A1HPGDTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |