Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355595 | 0.92 | POLB (0.54) | PTPN2PTPN1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL13586029 | 0.91 | PTPN2 (0.44) | PTPN2PTPN1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL4538215 | 0.89 | PTPN2 (0.45) | PTPN2PTPN1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL13586060 | 0.89 | SMN1; SMN2 (0.47) | PTPN2PTPN1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL4357579 | 0.89 | PTPN2 (0.44) | PTPN2PTPN1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL4356473 | 0.88 | PTPN2 (0.43) | PTPN2PTPN1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL4349922 | 0.88 | PTPN2 (0.43) | PTPN2PTPN1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL4537918 | 0.88 | PTPN2 (0.43) | PTPN2PTPN1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL13586043 | 0.87 | NPY2R (0.43) | PTPN2PTPN1SMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL4530802 | 0.86 | LMNA (0.51) | PTPN2PTPN1SMN1; SMN2ALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |