SCHEMBL4538252

SCHEMBL4538252

CCCCc1ccc(C)c(O)c1CCCC.CCCCc1cccc(OC)c1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 6/20 0.69
PTGS2 P35354 4/20 0.69
ELANE P08246 4/20 0.51
CTSG P08311 1/20 0.51
PPARA Q07869 1/20 0.45
IDO1 P14902 1/20 0.44
CALM1 P0DP23 1/20 0.42
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GAA P10253 1/20 0.39
GFER P55789 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26680132 0.89 ALOX5 (0.77) ALOX5PTGS2ELANECTSGPPARA
SCHEMBL59746 0.87 ALOX5 (0.90) ALOX5PTGS2ELANECTSGPPARA
SCHEMBL29365570 0.87 ALOX5 (0.90) ALOX5PTGS2ELANECTSGPPARA
SCHEMBL7210177 0.85 ALOX5 (0.87) ALOX5PTGS2ELANECTSGPPARA
Alcohol SCHEMBL28456628 0.85 ALOX5 (0.87) ALOX5PTGS2ELANECTSGPPARA
SCHEMBL18586290 0.82 ALOX5 (1.00) ALOX5PTGS2ELANECTSGPPARA
SCHEMBL292318 0.82 ALOX5 (0.57) ALOX5PTGS2ELANECTSGTYR
Alcohol SCHEMBL28670004 0.82 TYR (0.46) ALOX5PTGS2ELANECTSGALDH1A1
Benzene SCHEMBL28669217 0.82 TYR (0.46) ALOX5PTGS2ELANECTSGPPARA
SCHEMBL62288 0.82 TYR (0.49) ALOX5PTGS2ELANECTSGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7309727-A None JP disclosed
US-10307366-B2 Composition and related method for inhibiting moisture loss from skin ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) 2019-06-04 US disclosed
US-20190160117-A1 METHOD AND TOPICAL COMPOSITION FOR MODIFICATION OF A SKIN MICROBIOME ACCESS BUSINESS GROUP INTERNATIONAL LLC 2019-05-30 US disclosed
US-20170252293-A1 COMPOSITION AND RELATED METHOD FOR INHIBITING MOISTURE LOSS FROM SKIN ACCESS BUSINESS GROUP INTERNATIONAL LLC 2017-09-07 US disclosed
US-8623335-B2 Scar and rosacea and other skin care treatment composition and method WADDINGTON TAUNA ANN (US) 2014-01-07 US disclosed
US-20090068128-A1 SCAR AND ROSACEA AND OTHER SKIN CARE TREATMENT COMPOSITION AND METHOD WADDINGTON TAUNA A 2009-03-12 US disclosed
US-6419962-B1 PLANT EXTRACT IN CARRIER SHISEIDO COMPANY, LTD. (JP) 2002-07-16 US disclosed
JP-H07309727-A HAIR-TREATING AGENT HOYU CO LTD 1995-11-28 JP disclosed
US-4980215-A FIBROUS WEB, WICKING ALDINE TECHNOLOGIES, INC. (US) 1990-12-25 US disclosed