SCHEMBL453842

SCHEMBL453842

[Li]C[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL18050903 0.75 ALDH1A1 (0.50)
SCHEMBL31297208 0.62
SCHEMBL31297206 0.62
SCHEMBL12802155 0.62
SCHEMBL85727 0.59
SCHEMBL152107 0.59
SCHEMBL3300416 0.59
Iodide SCHEMBL25276934 0.56
SCHEMBL2971447 0.56
SCHEMBL5080529 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673446-A1 FLOW CHEMISTRY PROCESS FOR PREPARING AZA-BICYCLIC HETEROARYL COMPOUNDS Actinogen Medical Limited (AU) 2026-01-07 EP claimed
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 WO claimed
US-20250100951-A1 SELECTIVE AND LONG-LIVED SINGLE COMPONENT HETEROGENEOUS ETHYLENE TRIMERIZATION CATALYSTS ENABLED BY SURFACE LITHIATION UCHICAGO ARGONNE, LLC (US) 2025-03-27 US claimed
CN-119463184-A Trialkoxy functionalized polysiloxane, and preparation method and application thereof 杭州师范大学 2025-02-18 CN claimed
WO-2025021115-A1 POLYSUBSTITUTED PYRROLIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海闻耐医药科技有限公司 2025-01-30 WO claimed
CN-119080845-A Organic iron catalyst and preparation method and application thereof 浙江科技大学 2024-12-06 CN claimed
US-20240376024-A1 METHOD FOR PREPARING DEUTERATED CHEMICAL BY MEANS OF DEUTERATION REACTION OF CARBON-HYDROGEN BOND WITH DEUTERIUM GAS UNDER CATALYSIS OF ALKALI FUDAN UNIVERSITY (CN) 2024-11-14 US claimed
WO-2024178474-A1 FLOW CHEMISTRY PROCESS FOR PREPARING AZA-BICYCLIC HETEROARYL COMPOUNDS Actinogen Medical Limited (AU) 2024-09-06 WO claimed
US-12071418-B2 Processes for preparation of dapagliflozin or its solvates or co-crystals thereof LAURUS LABS LIMITED (IN) 2024-08-27 US claimed
CN-118271352-A Preparation method of rare earth complex 中国石油天然气股份有限公司 2024-07-02 CN claimed
US-20010018397-A1 Comprising reaction product of a cyclic siloxane and an organometallic compound such as sec-butyllithium; for making polymethyl methacrylate with high content of isotactic triads ELF ATOCHEM S.A. (FR) 2001-08-30 US claimed
CN-1226555-A Antifungal agent, and preparation method and intermediate thereof 1999-08-25 CN claimed
EP-0870777-A2 Initiator system and process for the anionic (co)polymerisation of (meth)acrylic, vinylaromatic and/or dienic monomers ELF ATOCHEM S.A. (FR) 1998-10-14 EP claimed
US-5639882-A CHEMICAL INTERMEDIATES FOR FORMING VIRICIDES INHIBITING LENTIVIRUSES G. D. SEARLE & CO. (US) 1997-06-17 US claimed
US-5637707-A STEREOSELECTIVELY ADDING ORGANONETALLIC REAGENT BY NUCLEOPHILIC ADDITION TO KETONE COMPOUND G. D. SEARLE & CO. (US) 1997-06-10 US claimed
EP-0566556-B1 2-Substituted tertiary carbinol derivatives of 1,5-iminosugars as antiviral compounds SEARLE & CO (US) 1996-07-03 EP claimed
EP-0667346-A2 Azole antifungal agents, process for the preparation there of and intermediates Eisai Co., Ltd. (JP) 1995-08-16 EP claimed
EP-0566556-A1 2-Substituted tertiary carbinol derivatives of 1,5-iminosugars as antiviral compounds G.D. Searle &amp; Co. (US) 1993-10-20 EP claimed
US-5104950-A Using supported complex of rare earth halide, ether and alkali metal alkyl as polymerization catalyst PHILLIPS PETROLEUM COMPANY (US) 1992-04-14 US claimed
US-5021379-A Reacting inorganic lanthanum halide with ether, contacting intermediate with alkali metal alkyl compound, depositing reaction product to a support PHILLIPS PETROLEUM COMPANY (US) 1991-06-04 US claimed