SCHEMBL453847

SCHEMBL453847

COc1cc(C)c(N)cc1N

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.60
POLB P06746 2/20 0.60
GAA P10253 4/20 0.59
GFER P55789 1/20 0.59
ALDH1A1 P00352 9/20 0.52
CYP3A4 P08684 4/20 0.52
HSD17B10 Q99714 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
TSHR P16473 2/20 0.48
MAPK1 P28482 2/20 0.48
PKM P14618 1/20 0.45
MAPT P10636 2/20 0.45
MEN1 O00255 1/20 0.45
THRB P10828 1/20 0.45
KMT2A Q03164 1/20 0.45
ALOX15 P16050 2/20 0.44
CYP1A2 P05177 1/20 0.44
CASP7 P55210 1/20 0.44
HIF1A Q16665 1/20 0.44
S100B P04271 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29540409 1.00 L3MBTL1 (0.60) L3MBTL1POLBGAAGFERALDH1A1
SCHEMBL9520839 0.90 L3MBTL1 (0.60) L3MBTL1POLBGAAGFERALDH1A1
SCHEMBL525676 0.90 L3MBTL1 (0.60) L3MBTL1POLBGAAGFERALDH1A1
SCHEMBL30723004 0.90 L3MBTL1 (0.60) L3MBTL1POLBGAAGFERALDH1A1
Hydrochloric Acid SCHEMBL3333737 0.88 L3MBTL1 (0.58) L3MBTL1POLBGAAGFERALDH1A1
SCHEMBL8080817 0.87 L3MBTL1 (0.56) L3MBTL1POLBGAAGFERALDH1A1
SCHEMBL29666518 0.87 POLB (0.61) L3MBTL1POLBGAAGFERALDH1A1
SCHEMBL1225409 0.87 POLB (0.61) L3MBTL1POLBGAAGFERALDH1A1
SCHEMBL4245018 0.86 GAA (0.51) L3MBTL1POLBGAAGFERALDH1A1
SCHEMBL1707894 0.85 POLB (0.54) L3MBTL1POLBGAAGFERALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2882822-B1 HYBRID THERMOPLASTIC GELS AND THEIR METHOD OF MAKING COMMSCOPE TECHNOLOGIES LLC (US) 2019-10-30 EP claimed
US-10058001-B2 Hybrid thermoplastic gels and their methods of making COMMSCOPE TECHNOLOGIES LLC (US) 2018-08-21 US claimed
US-20170311468-A1 HYBRID THERMOPLASTIC GELS AND THEIR METHODS OF MAKING ARRIS ENTERPRISES LLC (F/K/A ARRIS ENTERPRISES, INC.) 2017-10-26 US claimed
EP-2882822-A1 HYBRID THERMOPLASTIC GELS AND THEIR METHOD OF MAKING Tyco Electronics Coroporation (US) 2015-06-17 EP claimed
US-20140041893-A1 HYBRID THERMOPLASTIC GELS AND THEIR METHODS OF MAKING TYCO ELECTRONICS CORPORATION (US) 2014-02-13 US claimed
WO-2014025577-A1 HYBRID THERMOPLASTIC GELS AND THEIR METHOD OF MAKING TYCO ELECTRONICS CORPORATION (US) 2014-02-13 WO claimed
JP-4785024-B2 2011-10-05 JP claimed
EP-1494995-B1 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS PROCTER & GAMBLE (US) 2010-09-22 EP claimed
US-RE41549-E1 Dyes for keratin fibers, the dyes containing n-benzyl-p-phenylenediamine derivatives and novel n-benzyl-p-phenylenediamine derivatives WELLA AG (DE) 2010-08-24 US claimed
US-7771734-B2 Process to color and permanently restructure hair WELLA AG (DE) 2010-08-10 US claimed
EP-0955317-A1 Grafted maleimide-styrene-g-polypropylene copolymers used in rubber compounds for increasing hysteresis Bridgestone Corporation (JP) 1999-11-10 EP claimed
EP-0955329-A1 Centipede polymers grafted with hydrogenated block copolymers and polypropylene and gels thereof Bridgestone Corporation (JP) 1999-11-10 EP claimed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP claimed
US-5912296-A MALEATE AND ORGANIC DIAMINE FUNCTIONALIZED; SOFTNESS, HEAT RESISTANCE, DAMPING BRIDGESTONE CORPORATION (JP) 1999-06-15 US claimed
US-5910530-A MIXTUE OF A GRAFT COPOLYMER OF MALEATED BLOCK COPOLYMER, A MALEATED POLYPROPYLENE POLYMER, AND ORGANIC DIAMINE GRAFTING AGENT AND EXTENDER OIL; MOLDINGS HAVING HIGH HEAT RESISTANCE AND ELASTICITY; ELECTRONICS, CONSTRUCTION MATERIALS BRIDGESTONE CORPORATION (JP) 1999-06-08 US claimed
US-5905116-A Gels derived from extending grafted α-olefin-maleimide centipede polymers and polypropylene BRIDGESTONE CORPORATION (JP) 1999-05-18 US claimed
EP-0879832-A1 High damping gel derived from extending grafted elastomers and polypropylene Bridgestone Corporation (JP) 1998-11-25 EP claimed
EP-0879831-A1 An extended polymer composition derived from grafted elastomers and polypropylene Bridgestone Corporation (JP) 1998-11-25 EP claimed
US-4828771-A POLYEPOXIDES TOTO LTD. (JP) 1989-05-09 US claimed
US-4120913-A MIXING LIQUID EPOXY RESIN AND AROMATIC AMINE AND SOLID EPOXY RESIN POWDER WESTINGHOUSE ELECTRIC CORP. (US) 1978-10-17 US claimed