SCHEMBL525676

SCHEMBL525676

COc1cc(N)c(C)cc1N

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.60
POLB P06746 2/20 0.60
CYP3A4 P08684 4/20 0.55
TSHR P16473 2/20 0.55
MAPK1 P28482 2/20 0.55
GAA P10253 4/20 0.53
GFER P55789 1/20 0.53
ALDH1A1 P00352 9/20 0.52
PKM P14618 1/20 0.50
TDP1 Q9NUW8 3/20 0.48
HSD17B10 Q99714 2/20 0.48
NPC1 O15118 1/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
MEN1 O00255 1/20 0.45
THRB P10828 1/20 0.45
KMT2A Q03164 1/20 0.45
S100B P04271 1/20 0.44
TUBB4A P04350 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30723004 1.00 L3MBTL1 (0.60) L3MBTL1POLBCYP3A4TSHRMAPK1
SCHEMBL9520839 1.00 L3MBTL1 (0.60) L3MBTL1POLBCYP3A4TSHRMAPK1
Hydrochloric Acid SCHEMBL3333737 0.98 L3MBTL1 (0.58) L3MBTL1POLBCYP3A4TSHRMAPK1
SCHEMBL29540409 0.90 L3MBTL1 (0.60) L3MBTL1POLBCYP3A4TSHRMAPK1
SCHEMBL453847 0.90 L3MBTL1 (0.60) L3MBTL1POLBCYP3A4TSHRMAPK1
SCHEMBL29666518 0.87 POLB (0.61) L3MBTL1POLBCYP3A4TSHRMAPK1
SCHEMBL8080817 0.87 L3MBTL1 (0.56) L3MBTL1POLBCYP3A4TSHRMAPK1
SCHEMBL1225409 0.87 POLB (0.61) L3MBTL1POLBCYP3A4TSHRMAPK1
SCHEMBL926329 0.87 L3MBTL1 (0.67) L3MBTL1POLBCYP3A4TSHRMAPK1
SCHEMBL1707894 0.85 POLB (0.54) L3MBTL1POLBCYP3A4TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 843 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10639257-B2 Composition for colouring keratin fibres BEAUTY & BUSINESS S.P.A. (IT) 2020-05-05 US claimed
CN-105315666-B Transparent polymer film, electronic device including the same, and composition 三星电子株式会社 2020-03-10 CN claimed
CN-106009664-B Compositions, composites prepared therefrom, and films and electronic devices including the same 三星电子株式会社 2020-02-04 CN claimed
US-20190117541-A1 COMPOSITION FOR COLOURING KERATIN FIBRES BEAUTY & BUSINESS S.P.A. (IT) 2019-04-25 US claimed
US-9993413-B2 Keratin fibre dyeing composition BEAUTY & BUSINESS S.P.A. (IT) 2018-06-12 US claimed
US-9975997-B2 Compositions, composites prepared therefrom, and films and electronic devices including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-22 US claimed
US-20170258695-A1 KERATIN FIBRE DYEING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2017-09-14 US claimed
US-20160280857-A1 COMPOSITIONS, COMPOSITES PREPARED THEREFROM, AND FILMS AND ELECTRONIC DEVICES INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-09-29 US claimed
US-20160009862-A1 TRANSPARENT POLYMER FILM AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-01-14 US claimed
US-7419656-B2 Mixture containing phenylenediamine compound KAO CORPORATION (JP) 2008-09-02 US claimed
US-4865619-A Use, as a coupler, of 2,4-diamino-1,3-dimethoxybenzene or one of its salts, in combination with oxidation dye precursors, for dyeing human hair, hair dyeing composition containing the said coupler and process for preparing the said coupler L'OREAL (FR) 1989-09-12 US claimed
US-4865617-A Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers L'OREAL (FR) 1989-09-12 US claimed
US-4865618-A New chloro-meta-phenylenediamines, their use as couplers in the oxidation dyeing of keratinous fibres, dyeing compositions for hair containing these compounds and dyeing process using the said L'OREAL (FR) 1989-09-12 US claimed
EP-0317943-A2 Polymers prepared from 4,4'-bis-[2-(3,4-(dicarboxyphenyl) hexafluoroisopropyl] diphenyl ether dianhydride HOECHST CELANESE CORPORATION (US) 1989-05-31 EP claimed
US-4828568-A N-(2,4-DIHYDROXYBENZYLIDENE)AMINO COMPOUNDS AS PRIMARY COUPLERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1989-05-09 US claimed
EP-0295474-A1 Chlorometaphenylenediamines, their use as coupling agents in oxydation colouring of keratinic fibres, colourity compositions for hair containing these compounds and colouring process using these compositions L'OREAL (FR) 1988-12-21 EP claimed
EP-0294669-A1 Metaphenylendiamines, process for their preparation, intermediate compounds and use of these metaphenylendiamines as couplers in oxydative colouring of keratinic fibres especially of human hair L'OREAL (FR) 1988-12-14 EP claimed
US-4692166-A OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE L'OREAL (FR) 1987-09-08 US claimed
US-4684371-A Oxidation hair dyes comprising m-phenylenediamine derivatives as coupling components HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1987-08-04 US claimed
US-4575377-A Oxidation hair dyes comprising resorcinol derivatives as coupling components HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-03-11 US claimed