Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537910 | 0.79 | PARP1 (0.46) | BRD4PARP1MAPTKDM4EKMT2A | |
| SCHEMBL8051296 | 0.76 | PARP1 (0.46) | BRD4PARP1RETMAPTKMT2A | |
| SCHEMBL16502119 | 0.73 | PARP1 (0.46) | BRD4PARP1RETMAPTKMT2A | |
| SCHEMBL534330 | 0.73 | PARP1 (0.50) | BRD4PARP1RETMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL28064657 | 0.71 | PARP1 (0.49) | BRD4PARP1RETMAPTKMT2A | |
| SCHEMBL3578437 | 0.71 | TUBB4A (0.43) | PARP1 | |
| SCHEMBL13343596 | 0.71 | TUBB4A (0.43) | PARP1 | |
| SCHEMBL23676438 | 0.71 | HSD17B10 (0.39) | PARP1ADRA1DADRA1AADRA1BADRA2A | |
| SCHEMBL10140 | 0.69 | BRD4 (0.60) | BRD4PARP1RETKMT2AMMP12 | |
| SCHEMBL536589 | 0.67 | PARP1 (0.64) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638007-A2 | DRUG DERIVATIVES | Redx Pharma Limited (GB) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012063085-A2 | DRUG DERIVATIVES | REDX PHARMA LIMITED (GB) | 2012-05-18 | — | — | WO | disclosed |